Cancer study may accidentally help researchers create usable blood stem cells
A new study shows that cancer-causing MLL gene may also push pluripotent stem cells to make hematopoietic stem cells, a strong step in the decades-long effort to make personalizable, durable blood stem cells.
Mutations in donors' stem cells may cause problems for cancer patients
A new study suggests that extremely rare, harmful genetic mutations present in healthy donors' stem cells -- though not causing health problems in the donors -- may be passed on to cancer patients receiving stem cell transplants, potentially creating health problems for the recipients. Among the concerns are heart damage, graft-versus-host disease and possible new leukemias.
Artificial muscle sheets transform stem cells into bone
Specifically programmed materials can, under specific conditions, encourage stem cells to transform into bone cells. To do this, scientists implemented a so-called shape-memory polymer in stem cell research.
First genomic study of puberty yields insights into development and cancer
In the first-ever genome-scale analysis of the puberty process in humans, researchers outline distinct and critical changes to stem cells in males during adolescence.
New protocol to generate intestinal organoids in vitro
Researchers have developed a new way to generate groups of intestinal cells that can be used, among others, to make disease models in the lab to test treatments for diseases affecting the gastrointestinal system. Using human induced pluripotent stem cells, this novel approach combined a variety of techniques that enabled the development of three-dimensional groups of intestinal cells called organoids in vitro, which can expand disease treatment testing in the lab using human cells.