SRI 68th Annual Scientific Meeting
SRI 68th Annual Scientific Meeting

Detailed Program

Please note - Information listed in the Detailed Agenda is subject to changes and continually being updated to reflect the most up to date information.

All times listed in Eastern Daylight Time (EDT).

3:00 p.m. - 6:30 p.m.

Registration 

 

7:00 a.m. - 7:15 p.m.

Registration

 

8:30 a.m. - 12:00 p.m.

Satellite Meetings

VARIOUS ROOMS

     

1:15 p.m. - 4:30 p.m.

Satellite Meetings

VARIOUS ROOMS

5:00 p.m. - 5:20 p.m.

Presidential Address

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5:25 p.m. - 6:00 p.m.

March of Dimes Developmental Biology Prize Presentation and Lecture

The March of Dimes and Richard B. Johnston, Jr., MD Prize in Developmental Biology honors an outstanding scientist who has profoundly advanced the science that underlies our understanding of pregnancy, parturition and prenatal development. The Prize is sponsored by the Society for Reproductive Investigation, whose mission to advance reproductive and women’s health care through outstanding basic, translational and clinical science and by training and mentoring future generations of investigators complements March of Dimes’ work to support healthy moms and strong babies. The recipients of the Prize are leaders in reproductive biology working on translational and actionable science that can develop into interventions or preventions that will improve the health of moms and babies everywhere.

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6:00 p.m. - 7:00 p.m.

President's New Investigator Plenary
Supported by the Past Presidents' Fund

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7:00 p.m. - 7:30 p.m

Awards Ceremony

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7:30 p.m. - 8:30 p.m.

Welcome Reception

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7:00 a.m. - 6:00 p.m.

Registration

 

8:00 a.m. - 10:00 a.m.

Concurrent Oral Presentations I

 

 

Clinical and Translational Perinatology I
Moderators:
Information Coming Soon

Room Coming Soon

8:00 a.m. - 8:15 a.m.

O-005: Molecular Mechanisms Underlying Selective Sorting of MiRNAs into Small Extracellular Vesicles in Placental Cells in Gestational Diabetes Mellitus (GDM)
Soumyalekshmi Nair, Andrew Lai, Nanthini Jayabalan, Dominic Guanzon, Katherin Scholz-Romero,David McIntyre, Martha Lappas, Carlos Salomon

 

8:15 a.m. - 8:30 a.m.

O-006: Associations of Dietary Glycemic Index and Load during Pregnancy with Blood Pressure, Placental Hemodynamic Parameters and the Risk of Gestational Hypertensive Disorders
Clarissa J Wiertsema, Rama J Wahab, Annemarie GMGJ Mulders, Romy Gaillard

 

8:30 a.m. - 8:45 a.m.

O-007: Metabolomic Signatures of Low and High Adiposity Neonates Differ Based on Maternal BMI
Begum Aydogan Mathyk, Brian Piccolo, Kartik Shankar, Perrie O'Tierney-Ginn

 

8:45 a.m. - 9:00 a.m.

O-008: Adult Offspring of Obese Mice Have Reduced Resistance Artery Vasodilator Responses
Ramón A Lorca, Julie A Houck, Jerad H Dumolt, Owen R Vaughan, Kelsey Barner, Theresa L Powell, Thomas Jansson, Lorna G Moore, Colleen G Julian

 

9:00 a.m. - 9:15 a.m.

O-009: The Impact of Pre-Pregnancy Maternal Lipid Metabolism on Neonatal Adiposity
Raziel Rojas-Rodriguez, Patrick M Catalano

 

9:15 a.m. - 9:30 a.m.

O-010: Highly Atherogenic Lipid Particles Are Associated with Preeclampsia (Pre-E) in Obese Women with Unexplained Infertility Who Conceived during Ovarian Stimulation with Intrauterine Insemination (OS-IUI)
Robert A Wild, Rodney K Edwards, David S Wrenn, Yan D Zhao, Karl R Hansen

 

9:30 a.m. - 9:45 a.m.

O-011: Frequency and Correlates of Severe Chronic Hypertension (CHTN) 5 - 7 Years after Pregnancy Complicated by Mild CHTN
Ayamo Gina Oben, Jeff Szychowski, Rachel Sinkey, Peter Ketch, Cooper Elkins, William Andrews, Alan Tita

 

9:45 a.m. - 10:00 a.m.

O-012: A Prognostic Model for Early Risk Stratification of Spontaneous Preterm Birth
Anadeijda Landman, Marjon de Boer, Marije Lamain-de Ruiter, Martijn Heymans, Arie Franx, Martijn Oudijk, Mireille Bekker, Wendy Koster

 

 

Gynecology I
Moderators: 
TBD

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8:00 a.m. - 8:15 a.m.

O-013: Loss of MIG-6 Results in Endometrial Progesterone Resistance and Endometriosis-Related Infertility through ERBB2 Overexpression
 Tae Hoon Kim, Jung-Yoon Yoo, Jung-Ho Shin, Ryan Marquardt, Ulrich Müller, Asgerally Fazleabas, Steven Young, Bruce Lessey, Ho-Geun Yoon, Jae-Wook Jeong

 

8:15 a.m. - 8:30 a.m.

O-014: The Role of ARID1a in Mediating Endometriosis Disease Progression
Valerie Flores, Tran Dang, Hugh S Taylor

 

8:30 a.m. - 8:45 a.m.

O-015: Endometriosis Is a Possible Risk Factor for Premature Cardiovascular Disease
Jessica N Blom, Maria P Velez, Chad McClintock, Jessica Pudwell, Susan Brogly, Olga Bougie

 

8:45 a.m. - 9:00 a.m.

O-016: Randomized, Placebo-Controlled Trial of Botulinum Toxin for Endometriosis-Associated Chronic Pelvic Pain: A Longitudinal Assessment
Pamela Stratton, Hannah K Tandon, Vy Phan, Jacqueline V Aredo,, Ninet Sinaii, Jay P Shah, Barbara I Karp

 

9:00 a.m. - 9:15 a.m.

O-017: Bleeding Patterns in Women with Endometriosis-Associated Pain Treated with Relugolix Combination Therapy: SPIRIT Program
Andrea S Lukes, Sawsan As-Sanie, Christian M Becker, Mauricio S Abrao, Claudia Mehedintu, Galyna Reznichenko, , Linda Giudice, Furong Wang, Viatcheslav G Rakov, Qurratul A Warsi

 

9:15 a.m. - 9:30 a.m.

O-018: Single-Cell Sequencing Reveals Novel Cell Type and Heterogeneous Non-Monoclonal Cell Populations in Human Leiomyomas
Jyoti Goad, Joshua Rudolph, Jian-Jun Wei, Serdar E Bulun, Debabrata Chakravarti, Aleksandar Rajkovic

 

9:30 a.m. - 9:45 a.m.

O-019: Long Noncoding RNA MIAT Modulates the Extracellular Matrix Deposition in Leiomyomas via Sponging MiR-29 Family
Tsai-Der Chuang, Derek Quintanilla, Drake Boos, Omid Khorram

 

9:45 a.m. - 10:00 a.m.

O-020: Reduction in Menstrual Blood Loss in Patients Treated with Relugolix Combination Therapy: LIBERTY Long-Term Extension Study
Ayman Al-Hendy, Andrea S Lukes, Alfred Poindexter III, Roberta Venturella, Claudio Villarroel, Rachel B Wagman, Yulan Li, Elizabeth A Stewart, Laura McKain

 
  Parturition I
Moderators: 
TBD

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8:00 a.m. - 8:15 a.m.

O-021: Upregulation of miR-877-3p and Downregulation of miR-186-3p in the Placentas of Patients with Idiopathic Preterm Birth
Duygu Mutluay, Xiaofang Guo, Ozlem Guzeloglu Kayisli, Frederick Schatz, Umit Kayisli, Charles Lockwood

 
 

8:15 a.m. - 8:30 a.m.

O-022: Iron-Dependent Apoptosis Causes Embryotoxicity in Inflamed and Obese Pregnancy
Allison L Fisher, Veena Sangkhae, Tomas Ganz, Elizabeta Nemeth

 
 

8:30 a.m. - 8:45 a.m.

O-023: A Broad Spectrum Chemokine Inhibitor Prevents Infection-Induced Myometrial Inflammation and Activation
Adam Boros-Rausch, Tsung-Yen Wu, Kristina Adams Waldorf, Oksana Shynlova, Stephen Lye

 
 

8:45 a.m. - 9:00 a.m.

O-024: Exposure to Experimental Fetal Inflammatory Response Syndrome Results in IL-6 Dependent Upregulation of Interferon Lambda Expression and Subsequent Loss of Neonatal Paneth Cells
Sarah Nichole Watson, Huiyu Gong, Brian Juber, Steven Mcelroy

 
 

9:00 a.m. - 9:15 a.m.

O-025: Establishment of a Mouse Uterine Explant Model to Study Inflammation in Pregnancy and Parturition
Madeline Snedden, Chandrashekara Kyathanahalli, Emmet Hirsch

 
 

9:15 a.m. - 9:30 a.m.

O-026: Inflammatory-Related Mir-612 Is Increased in Circulating Exosome-Like Vesicles from Women Undergoing Preterm Birth
 Bruna Ribeiro de Andrade Ramos, Júlia Abbade Tronco, Márcio de Carvalho, Patrícia Pintor dos Reis, Juliano Coelho da Silveira, Márcia Guimarães da Silva

 
 

9:30 a.m. - 9:45 a.m.

O-027: Dose-Response Profile of a Novel Anti-Interleukin-1 Therapeutic, Rytvela, for Prevention of Preterm Birth
Tiffany Habelrih, Sarah-Eve Loiselle, France Côté, Xin Hou, Christiane Quiniou, Sylvain Chemtob

 
 

9:45 a.m. - 10:00 a.m.

O-028: Placenta Serum Amyloid A-2 (SAA-2) Plays an Important Role in Maternal Inflammation-Induced Adverse Fetal Outcomes
Yang Liu, Jin Liu, Anguo Liu, Irina Burd, Lei Jun

 
  Placenta I
Moderators: 
TBD

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8:00 a.m. - 8:15 a.m.

O-029: A Microphysiological Model of Human Trophoblast Invasion during Early Embryo Implantation
Sneha Mani, Ju Young Park, Geremy Clair, Cassidy Blundell, Rachel Young, Jessica Kanter, Scott Gordon, Yoon-Suk Yi, Dan Dongeun Huh, Monica Mainigi

 
 

8:15 a.m. - 8:30 a.m.

O-030: The Utero-Placental Vascular Skeleton: A New Image Processing Technique to Estimate Utero-Placental Vascular Morphologic Development and the Association with Maternal Hemodynamic Adaptation to Pregnancy
Eline S de Vos, Anton HJ Koning, Régine PM Steegers-Theunissen, Sten P Willemsen, Bas B van Rijn, Eric AP Steegers, Annemarie GMGJ Mulders

 
 

8:30 a.m. - 8:45 a.m.

O-031: Placental Cell-Specific Extracellular Vesicle Profiles from Syncytiotrophoblasts and Extravillous Trophoblasts in the First Trimester
Terry Morgan, Mayu Morita, Leslie Myatt

 
 

8:45 a.m. - 9:00 a.m.

O-032: Impaired Cell Polarity and Bi-Directional Endothelial Cell-Matrix Interactions Mediate Disrupted Fetoplacental Angiogenesis
Shuhan Ji, Diane Gumina, Emily J Su

 
 

9:00 a.m. - 9:15 a.m.

O-033: Activation of Amnion Signaling during Intrauterine Inflammation Is TNF-Dependent
Pietro Presicce, M Cappelletti, M Morselli, P Senthamaraikannan, L Miller, M Pellegrini, A Jobe, C Chougnet, S Kallapur

 
 

9:15 a.m. - 9:30 a.m.

O-034: Role of GATA2 and GATA3 in Syncytiotrophoblast Development during Mammalian Placentation
Ananya Ghosh

 
 

9:30 a.m. - 9:45 a.m.

O-035: Females Are Not Just ‘Protected’ Males: Sex-Specific Vulnerabilities in Placenta and Brain after Prenatal Immune Disruption
Amy E Braun, Pamela A Carpentier, Brooke A Babineau, Aditi R Narayan, Michelle L Kielhold, Hyang Mi Moon, Jennifer Su, Vidya Saravanapandian, Theo D Palmer

 
 

9:45 a.m. - 10:00 a.m.

O-036: Derivation of Human Trophoblast Stem Cells from Pluripotent Stem Cells to Model Early Placental Development
Francesca Soncin, Mariko Horii, Rob Morey, Tony Buy, Daniela Requena, Virginia Chu Cheung, Omar A Farah, Don Pizzo, Mana M Parast

 
 

Maternal Biology and Health
Moderators: 
TBD

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8:00 a.m. - 8:15 a.m.

O-037: Percutaneous Electrical Stimulation of Skeletal Muscle Attenuates Insulin Resistance in Pregnant Rats with Diet-Induced Obesity
David Coggin-Carr, Keara McElroy-Yaggy, Paul D Taylor, Anna L David, Elisabet Stener-Victorin, Tom Jetton

 
 

8:15 a.m. - 8:30 a.m.

O-038: Seasonality and the Immune System during Pregnancy: Impact of Seasonal Affective Disorder
Cindy Xin Wen Zhang, Robert Levitan, Stephen Matthews

 
 

8:30 a.m. - 8:45 a.m.

O-039: Estradiol Stimulates Pregnancy-Dependent H2S Biosynthesis in Human Uterine Artery Endothelial Cells via ERα/ERβ-Mediated Upregulation of CBS Transcription
Jin Bai, Thomas J Lechuga, Qian-rong Qi, Yi-hua Yang, Quan-wei Zhang, Yan Li, Dong-bao Chen

 
 

8:45 a.m. - 9:00 a.m.

O-040: Placental MiRNAs Predicted to Target Insulin Signaling Pathways Are Associated with Maternal Insulin Resistance in Late Pregnancy
Fernanda L Alvarado Flores, William Beyer, Tomoko Kaneko-Tarui, Tianjiao Chu, Yoel Sadovsky, Patrick Catalano, Perrie O’Tierney-Ginn

 
 

9:00 a.m. - 9:15 a.m.

O-041: Clot Formation Potential in the Late Pregnant and Postpartum Woman
Elizabeth Barker, Ira Bernstein, Thomas Orfeo, Kelley McLean, Maria Cristina Bravo

 
 

9:15 a.m. - 9:30 a.m.

O-042: Identification and Isolation of Rare Microchimeric Cells in Maternal and Cord Blood.
Whitney Harrington, Yonghou Jiang,  Whitney Harrington, John Houck, Marc Carlson, Stephen McCartney, Kelsey Olerich, Sami B Kanaan, J Lee Nelson, Raj Shree

 
 

9:30 a.m. - 9:45 a.m.

O-043: Women with Adverse Pregnancy Outcomes Have Higher Risk of Midlife Stroke: The PATH Study.
Eliza C Miller, Natalie A Bello, Rindcy Davis, Alexander M Friedman, Mitchell SV Elkind, Ronald Wapner, Sarah E Tom

 
 

9:45 a.m. - 10:00 a.m.

O-044: Isolating Mechanisms on Future Cardio-Renal Risk in Mothers with Complicated Pregnancy
Kimberley J Botting, Wen Tong, Youguo Niu, Tessa A Garrud, Lin Zhang, Sage G Ford, Qiang Lyu, Olga V Patey, Dino A Giussani

 
 

Reproductive Biology I
Moderators: 
TBD

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8:00 a.m. - 8:15 a.m.

O-045: Small Non‑Coding RNA Biotypes in the Human Preimplantation Embryo
Sophie Petropoulos,  Stewart J Russell, Cheng Zhao, Karen Menezes, Clifford L Librach

 
 

8:15 a.m. - 8:30 a.m.

O-046: Screening Putative Haplo-Essential Translation Genes for Contribution to Early Reproductive Failure
Luwam Ghidei, Denise Lanza, Lauryl M J Nutter, Pilar Cacheiro, Violeta Munoz-Fuentes, Jason Heaney

 
 

8:30 a.m. - 8:45 a.m.

O-047: Elucidating the Role of FOXO3 in Regulating Ovarian Reserve and Function in Humans
Caterina Clementi, Karen Hunter Cohn, Genevieve Galarneau, Piraye Yurttas Beim

 
 

8:45 a.m. - 9:00 a.m.

O-048: Loss of Ovarian Expression of the Noncoding RNA H19 Promotes Susceptibility to Doxorubicin-Induced DNA Damage
Amanda N Kallen, Pingping Lu, Jing Wang, Joshua Johnson

 
 

9:00 a.m. - 9:15 a.m.

O-049: Novel Anti-Mullerian Hormone Receptor 2 Binding Peptide (AMHR2BP) Modulates Oocyte Function In Vivo
Laura Detti, Ghassan M Saed

 
 

9:15 a.m. - 9:30 a.m.

O-050: Aneuploidy in Human Embryos May Elicit a Premature Differentiation Response in the Inner Cell Mass
Angel Martin, Francisco Dominguez, Alicia Quiñonero, Carmina Vidal, Amparo Mercader, Fernanda Insua, Maria Jose De los Santos

 
 

9:30 a.m. - 9:45 a.m.

O-051: Bromodomain Extraterminal (BET) Family Inhibitor JQ1 Inhibits Nuclear Maturation and Cytoplasmic Organization of Oocytes
Keerthana Karunakar Poojary, Sandhya Kumari, Satish K Adiga, Guruprasad Kalthur

 
 

9:45 a.m. - 10:00 a.m.

O-052: Opposite Effects of LH/PKA/MTOR and AMPK Signaling on Induction of Autophagy in Luteal Cells
Emilia Przygrodzka, Michele R Plewes, Guojuan Li, John S Davis

 

10:00 a.m. - 10:30 a.m.

Coffee Break

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10:30 a.m. - 12:30 p.m.

Mini-Symposia I

 

 

Stem Cell Therapy of Reproductive Disorders
*Interactive Session
Moderators: 
Ayman Al-Hendy, MD, PhD
Sonia Herrais, PhD

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10:30 a.m. - 10:55 a.m.

Opportunities and Challenges in Regenerative Therapies
Sonia Herriaz, PhD

 

10:55 a.m. - 11:20 a.m.

Stem Cell and Gene Therapy of Ovarian Infertility: from Bench to Rodents to Women, and Back
Ayman Al-Hendy, MD, PhD

 

11:20 a.m. - 11:45 a.m.

Cell Therapy of Asherman Syndrome and Endometrial Atrophy
Carlos Simon, MD, PhD

 

11:10 a.m. - 12:10 p.m.

Stem cell therapies for male infertility: ready for the clinic
Kyle Orwig, PhD

 

12:10 p.m. - 12:30 p.m.

Session Q&A

 

 

Pregnancy – A Lost Opportunity to Screen
Moderators: 
Sandy T. Davidge, PhD, FCAHS
Laura A. Magee, MD, FRCPC, MSc, FACP, FRCOG

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10:30 a.m. - 10:55 a.m.

Pregnancy Complications and the Life Course – Implications for the Child
Lucilla Poston, PhD

 

10:55 a.m. - 11:20 a.m.

Placental Insufficiency and Impact on Fetal Development
Emily J. Su, MD

11:20 a.m. - 11:45 a.m.

Adverse Pregnancy Outcomes Screening and Long Term Maternal Health
Fergus McCarthy, MSc, PhD

11:45 a.m. - 12:10 p.m.

Patient-Reported Outcomes and the Feasibility of Tracking Long-Term Cardiovascular Disease Outcomes – The Preeclampsia Foundation Registry
Mayri Leslie

 

12:10 p.m. - 12:30 p.m.

Session Q&A

 
  SRI – PRS Joint Session: Interaction at the Maternal-Fetal Interface and Origins of Child Health and Disease
Moderators: 
Maide Ozen, MD
Yoel Sadovsky, MD

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10:30 a.m. - 10:55 a.m.

Implications of Immunoperinatology Research on Neonatal and Lifetime Health
Maide Ozen, MD

 

10:55 a.m. - 11:20 a.m.

Multidisciplinary, Multiplatform Approaches to Unravel the Mechanisms of Adverse Pregnancy Outcomes
Nima Aghaeepour, PhD

 

11:20 a.m. - 11:45 a.m.

Feto-Placental Interface, What Did We Learn?
Yoel Sadovsky, MD

 

11:45 a.m. - 12:10 p.m.

Gaps in Knowledge in Understanding the Immunobiology and Immunopathology of Pregnancy and Future Directions
Ana Claudia Zenclussen, PhD

 

12:10 p.m. - 12:30 p.m.

 Session Q&A

 
  Embryo Aneuploidy and Mosaicism: Implications for Reproduction and ART
Moderators: 
Robert N. Taylor, MD, PhD
Mindy S. Christianson, MD

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10:30 a.m. - 10:55 a.m.

Understanding Aneuploidy
Pat Hunt, PhD

 

10:55 a.m. - 11:20 a.m.

Developmental Potential of Aneuploid Human Embryos Beyond Implantation
Magdalena Zernicka-Goetz, PhD

 

11:20 a.m. - 11:45 a.m.

Assessment of Aneuploidy and Mosacisim in Human Embryos: Promises and Pitfalls of Molecular Approaches and Study Designs
Richard T. Scott Jr., MD

 

11:45 a.m. - 12:10 p.m.

New Insights From Clinical NIPT Data Regarding Human Aneuploidy and Mosaicism
Diana W. Bianchi, MD

 

12:10 p.m. - 12:30 p.m.

 Session Q&A

 
  Translational Research: Diagnostic Innovations in Reproduction
Moderators:
Erica Marsh
Patricia Jimenez

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10:30 a.m. - 10:55 a.m.

Title TBD
Hugh S. Taylor, MD

 

10:55 a.m. - 11:20 a.m.

Title TBD
Louise Laurent

 

11:20 a.m. - 11:45 a.m.

Title TBD
Denny Sakkas

 

11:45 a.m. - 12:10 p.m.

Title TBD
Nardhy Gomez-Lopez

 

12:10 p.m. - 12:30 p.m.

 Session Q&A

 
  Reproduction Meets Imaging
Moderators: 
Hari Eswaran, PhD
Jessica Ramella-Roman, PhD

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10:30 a.m. - 10:55 a.m.

In Vivo Imaging of Reproductive Dynamics in the Mouse Oviduct
Shang Wang, PhD

 

10:55 a.m. - 11:20 a.m.

Active Fluctuations Modulate Nuclear Dynamics in Oocytes
Marie-Helene Verlhac, PhD

 

11:20 a.m. - 11:45 a.m.

Quantitative Ultrasound of the Cervix in Pregnancy: Today & Tomorrow
Helen Feltovich, MD

 

11:45 a.m. - 12:10 p.m.

Preventing Postpartum Depression: An Intergenerational fMRI Clinical Trial
Kristen Mackiewicz Seghete, PhD

 

12:10 p.m. - 12:30 p.m.

 Session Q&A

 

12:45 p.m. - 1:45 p.m.

Lunch and Learn Symposium I 
*Boxed lunches are available and complimentary through the Registration Deadline only.

 

 

Big Data and the Impact on Scientific Success
Moderators: 

Dorothy K. Sojka, PhD
Aleksandar K. Stanic, MD, PhD

Room Coming Soon

12:45 p.m. - 1:00 p.m.

Introduction to Big Data Analysis
Piraye Yurttas Beim, PhD

 

1:00 p.m. - 1:15 p.m.

Multi-Omics Approach in Uterine Fibroids Research
Benedikt Kessler, PhD

 

1:15 p.m. - 1:30 p.m.

Systems Biology Study to Puzzle out Preterm Birth with an Integrated-Omics Approach
Nanbert Zhong, MD, PhD 

 

1:30 p.m. - 1:45 p.m.

Session Q&A

 

12:45p.m. - 1:45 p.m.

Lunch and Learn Symposium II 
*Boxed lunches are available and complimentary through the Registration Deadline only.

 

 

NIH and Reproductive Medicine
Moderators: 

Irina Burd, MD, PhD​
Emre Seli, MD

Room Coming Soon

12:45 p.m. - 1:00 p.m.

NICHD Strategic Planning Update
Diana Bianchi, MD

 

1:00 p.m. - 1:15 p.m.

Strategies for Obtaining NIH Extramural Funding
Lisa Halvorson, MD

 

1:15 p.m. - 1:30 p.m.

Life as an Intramural NIH Researcher
Alan DeCherney, MD

 

1:30 p.m. - 1:45 p.m.

Session Q&A

 

2:00 p.m. - 3:30 p.m.

Concurrent Oral Presentations II

 

 

 Developmental Programming I
Moderators: 
TBD

Room Coming Soon

2:00 p.m. - 2:15 p.m.

O-053: Epigenetic Effects of N-acetylcysteine on H2S-Mediated Protection Against Fetal Origins of Vascular Disease.
A A Paz, T A Garrud, E Peñaloza, F Vega-Tapia, S G Ford, Y Niu, B J Krause, D A Giussani

 

2:15 p.m. - 2:30 p.m.

O-054: Placental Endocrine Malfunction Causes Sex Specific Changes in Metabolic Organs of Fetal and Adult Mouse Offspring
Efthimia Christoforou,  Panayiotis Laouris, Jorge Lopez-Tello, Marta Ibanez Lligona, Hannah Yong, Alison Forhead, Amanda Sferruzzi-Perri

 

2:30 p.m. - 2:45 p.m.

O-055: Maternal Obesity Upregulates Fetal Heart Pparg Expression with Consequences for Later Life Cardiac Metabolic and Contractile Function in Mice
O R Vaughan, J Chan, L Cox, V Ferchaud-Roucher, F Rosario, J EB Reusch, A C Keller, T L Powell, T Jansson

 

2:45 p.m. - 3:00 p.m.

O-056: Defining the Role of the Hypothalamic Pituitary Adrenal Axis in the Relationship between Fetal Growth and Adult Cardiometabolic Outcomes
Wrivu N Martin, Carol A Wang, Stephen J Lye, Rebecca M Reynolds, Stephen G Matthews

 

3:00 p.m. - 3:15 p.m.

Speaker Information Coming Soon!

 

3:15 p.m. - 3:30 p.m.

Speaker Information Coming Soon!

 
 

Fetus I
Moderators: 
TBD 

Room Coming Soon

2:00 p.m. - 2:15 p.m.

O-057: Hypoxemia Prevents Insulin Mediated Suppression of Gluconeogenic Gene Expression in the Fetal Liver during Hypoglycemia
Priya Mukherjee, Amanda Jones, Paul Rozance, Brown Laura, Sean Limesand, Stephanie Wesolowski

 

2:15 p.m. - 2:30 p.m.

O-058: Maternal Obesity Induces Fetal Sheep Hepatic Oxidative Stress (OS) and Mitochondrial Damage Predominantly in the Right Lobe
Susana P Pereira, Luis F Grilo, Mariana S Diniz, Carolina Tocantins, João D Martins, Stephen Ford, Peter W Nathanielsz, Paulo J Oliveira

 

2:30 p.m. - 2:45 p.m.

O-059: Impaired Autonomic Control of Heart Rate Variability during Acute Stress in the Chronically Hypoxic Fetus
N Hafiz, B J Allison, N Itani, K J Botting, Y Niu, C C Lees, C J Shaw, D A Giussani

 

2:45 p.m. - 3:00 p.m.

O-060: RNAseq of Amniotic Fluid Reveals Activation of the Innate Immune Response and Differential Expression of Brain Transcripts in Fetuses with Cytomegalovirus Infection
Lisa Hui, Luc de Catte, Neeta Vora, Sally Beard, Jovana Maksimovic, Alicia Oshlac, Susan P Walker, Natalie Hannan

 

3:00 p.m. - 3:15 p.m.

O-061: Uterine Fibroids Associated with Lower Fetal Fraction and Indeterminate NIPS Results in Non-Obese Subjects
Teodora Kolarova, Hayley MacKinnon, Jaclynne Hedge, Christina Lockwood, Raj Shree

 

3:15 p.m. - 3:30 p.m.

O-062: Cervical Gene Delivery of the Antimicrobial Peptide Human β Defensin 3 (HBD3) Reduces Perinatal Neuroinflammation in a Mouse Model of Ascending Infection-Associated Preterm Birth
Ashley K Boyle, Natalie Suff, Simon N Waddington, Donald Peebles

 
 

Preeclampsia I
Moderators: 
TBD

Room Coming Soon

2:00 p.m. - 2:15 p.m.

O-063: Functional Enrichment Analysis of Differentially Expressed Transcripts/Genes of Medium/Large STBEVs Identified Potentially Dysregulated Pathways in Early Onset Preeclampsia (EOPE)
Toluwalase Awoyemi, Adam Cribbs, Wei Zhang, Chris Redman, Manu Vatish

 

2:15 p.m. - 2:30 p.m.

O-064: Proinflammatory and Anti-Inflammatory Cytokine Responses by Decidua T Cells in Preeclampsia
Ai-ris Yonekura Collier, Dan H Barouch

 

2:30 p.m. - 2:45 p.m.

O-065: Impact of Preeclampsia on Polarization and Functionality of Hofbauer Cells
Monika Horvat Mercnik, Carolin Schliefsteiner, Christian Wadsack

 

2:45 p.m. - 3:00 p.m.

O-066: CD4 T Cells Deficiency Enhances Internal Carotid Artery Constriction in Postpartum Mice: The Role of Nitric Oxide
Natalia I Gokina, Rebecca I Fairchild, Kirtika Prakash, Nicole M DeLance, Elizabeth A Bonney

 

3:00 p.m. - 3:15 p.m.

O-067: Noninvasive Prediction of Preeclampsia in Pregnancy with Circulating RNA
Mira N Moufarrej, Ronald J Wong, Ana A Campos, Cecele C Quaintance, Rene V Sit, Michelle Tan, Norma F Neff, Maurice L Druzin, Virginia D Winn, Gary M Shaw, David K Stevenson, Stephen R Quake

 

3:15 p.m. - 3:30 p.m.

O-068: Circulating SIGLEC6 Is Deranged in Preeclampsia and May Be a Biomarker of Disease Severity
Tu'uhevaha J Kaitu'u-Lino, Susan P Walker, Teresa M MacDonald, Catherine Cluver, Roxanne Hastie, Lina Bergman, Lesley McCowan, Rennae Taylor, Emerson Keenan, Natalie J Hannan, Ping Cannon, Tuong-Vi Nguyen, Manju Kandel, Stephen Tong

 
 

Gynecology II
Moderators: 
TBD

Room Coming Soon

2:00 p.m. - 2:15 p.m.

O-069: Pregnancy Outcomes Following Routine Early Provision of IUD after First Trimester Induced Abortion - 5-year Follow-Up of a Randomized Controlled Trial
Oskari M Heikinheimo, Elina Pohjoranta, Satu Suhonen, Maarit Mentula, Mika Gissler

 

2:15 p.m. - 2:30 p.m.

O-070: Towards 3-D Imaging of the Murine Vagina
Diego R Gatica, Li Guang, J Quincy Brown, Kristin S Miller

 

2:30 p.m. - 2:45 p.m.

O-071 :A Meta-Analysis Investigation of Anti-Mullerian Hormone Trends in Survivors of Childhood Cancer
Allison Kumnick, Veronica Gomez-Lobo, Ninet Sinaii, Jacqueline Maher

 

2:45 p.m. - 3:00 p.m.

O-072: Euploid Miscarriage Is Associated with Lactobacillus spp. Deplete Vaginal Microbial Composition and Local Inflammation
Karen Grewal, Yun S Lee, Ann Smith, Jan J Brosens, Tom Bourne, Maya Al-Memar, Samit Kundu, David A MacIntyre, Phillip Bennett

 

3:00 p.m. - 3:15 p.m.

O-073: Anemia and Abnormal Uterine Bleeding Prevalence in the Environment, Leiomyomas, Latina and Adiposity Study (ELLAS)
Torie C Plowden, Anne Waldo, Anita Malone, Felix M Valbuena, Charo Ledon, Donna D Baird, Erica E Marsh

 

3:15 p.m. - 3:30 p.m.

O-074: Route of Myomectomy and Probability of Pregnancy or Live Birth
Sophia Anderson, Laine Thomas, Lauren Wise, Elizabeth A Stewart, COMPARE-UF Team

 
 

Parturition II
Moderators: 
TBD

Room Coming Soon

2:00 p.m. - 2:15 p.m.

O-075: Cell Free Fetal DNA (cffDNA) from Human Amnion Epithelial Cells Increase Inflammatory Load in Human Fetal Membrane Tissue
Chelsea Saito Reis, Samantha Oetjen, Claire Kendal-Wright

 

2:15 p.m. - 2:30 p.m.

O-076: Microbial Metabolites Compromise Epithelial Barrier Integrity: Potential Mechanisms by Which Non-Optimal Cervicovaginal Microbiota Lead to Preterm Birth
Kristin D Gerson, Yusra Gimie, Lauren Anton, Michal A Elovitz
 

 

2:30 p.m. - 2:45 p.m.

O-077: Single Cell Transcriptomics Identify Distinct Epithelial Populations in Early versus Late Pregnancy
Shanmugapriyaa Madhukaran, Anne Cooley, Gary Hon, Mala Mahendroo

 

2:45 p.m. - 3:00 p.m.

O-078: Essential Roles of Uterine Peristalsis by Cav1.2 in Reproduction and Adenomyosis in Mice
Mingzi Qu, Ping Lu, Christina Baer, Lawrence Lifshitz, Ronghua ZhuGe

 

3:00 p.m. - 3:15 p.m.

O-079: Differential Regulation of SOX Family Transcription Factors in the Pregnant and Labouring Mouse Myometrium
Nawrah Khader, Virlana Shchuka, Anna Dorogin, Oksana Shynlova, Jennifer Mitchell

 

3:15 p.m. - 3:30 p.m.

O-080: Intrauterine Infection Induced Preterm Labor Is Associated with Site-Specific Phosphorylation of Progesterone Receptor A in Myometrial Cells
Rachel A Wilson, Pietro Presicce, Monica Cappelletti, Alan Jobe, Senad Divanovic, Sing Sing Way, Claire Chougnet, Sam Mesiano, Suhas Kallapur

 
 

Reproductive Endocrinology and Infertility I
Moderators: 
TBD

Room Coming Soon

2:00 p.m. - 2:15 p.m.

O-081: Cumulus Cells Transcriptomic Biomarkers of Euploid Human Embryo Implantation
Cynthia Scott, Shiny Titus, Emre Seli

 

2:15 p.m. - 2:30 p.m.

O-082: Rapid Aneuploidy Testing in Reproduction Using Nanopore-Based Sequencing
Shan Wei,  Alexandre Djandji, Nataly Hoffman, Claudia Cujar, Refik Kayali, Cegniz Cinnioglu, Ronald Wapner, Mary D’Alton, Brynn Levy, Zev Williams

 

2:30 p.m. - 2:45 p.m.

O-083: Characterization of the Non-Classic Progesterone Receptor Membrane Component 2 (PGRMC2) during the Human Menstrual Cycle and In Vitro Decidualization
Yassmin Medina-Laver, Indra Diaz-Hernandez, Pilar Alama, Roberto Gonzalez-Martin, Andrea Palomar, Alicia Quiñonero, Francisco Dominguez

 

2:45 p.m. - 3:00 p.m.

O-084: Human Placenta Mesenchymal Stem Cells Derived Exosomes Successfully Reverse Infertility in Chemotherapy Induced Premature Ovarian Insufficiency Mouse Model
Esra Cetin, Hang-soo Park, Hiba Siblini, Ayman Al-Hendy

 

3:00 p.m. - 3:15 p.m.

O-085: An In Vivo Model of Human FSH Dysregulation in Obesity: Obese Women Exhibit Lower Serum FSH Levels in Response to Intravenous Recombinant FSH after GnRH Suppression
Katherine Kuhn, Thanh-Ha Luu, Andrew P Bradford, Luke Wittenberg, Nne-Omoji Nwobodo, Polotsky J Alex, Michael Wempe, PhD

 

3:15 p.m. - 3:30 p.m.

O-086: Different Immunoregulatory Components at the Decidua Basalis of Oocyte Donation Pregnancies
Kim van Bentem, Manon Bos, Carin van der Keur, Hanneke Kapsenberg, Lisa Lashley, Michael Eikmans, Marie-Louise van der Hoorn

 

3:30 p.m. - 4:00 p.m.

Coffee Break

 

4:00 p.m. - 5:30 p.m.

Poster Session I

 

5:45 p.m. - 6:30 p.m.

President's Distinguished Researchers Award I

 

Joan Steitz, PhD
Sterling Professor of Molecular Biophysics and Biochemistry
Yale School of Medicine

 

6:30 p.m. - 7:10 p.m.

Awards Ceremony

Room Coming Soon

 
  • 2020 Recipients
    • The DeCherney Society Lifetime Distinguished Service Award: Sarah Berga
    • The SRI Distinguished Scientist Award: Hugh Taylor
    • The President's Achievement Award: Kjersti Aagaard
    • The SRI Mentorship Award: Sarah Robertson
 
 
  • 2021 Recipients
    • DeCherney Society Lifetime Distinguished Service Award
    • SRI Mentorship Award
    • SRI Distinguished Scientist Award
    • SRI President’s Achievement Award
 

7:30 p.m. - 9:00 p.m.

Connection Corners

Room Coming Soon

 

7:00 a.m. - 7:00 p.m. 

Registration

 

7:00 a.m. - 8:00 a.m.

SRI Business Meeting
*Breakfast will be served and ALL SRI Members are invited to attend

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8:00 a.m. - 9:00 a.m.

President's Distinguished Researchers Award II

Room Coming Soon

Gregg L. Semenza, MD, PhD
C. Michael Armstrong Professor of Genetic Medicine
Johns Hopkins University School of Medicine

 

9:00 a.m. - 9:45 a.m.

Hot Topics & Awards Ceremony

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9:45 a.m. - 10:15 a.m.

Coffee Break

Room Coming Soon

10:15 a.m. - 11:45 a.m.

Concurrent Oral Presentations III

 

Epidemiology and Global Health
Moderators: 
TBD

Room Coming Soon

10:15 a.m. - 10:30 a.m.

 

O-087: Associations of Maternal Urinary Bisphenol and Phthalate Urine Concentrations in Pregnancy with Offspring Pubertal Development
Sophia Blaauwendraad, Romy Gaillard, Vincent Jaddoe

 

10:30 a.m. - 10:45 a.m.

 

O-088: Maternal Levels of Perfluoroalkyl Substances (PFAS) during Early Pregnancy in Relation to Preeclampsia Subtypes and Biomarkers of Preeclampsia Risk
Paige A Bommarito, Kelly K Ferguson, John D Meeker, Thomas F McElrath, David E Cantonwine

 

10:45 a.m. - 11:00 a.m.

 

O-089: Maternal Preconception Platelet Activation and Pregnancy Outcomes
Ashley Shea, Lauren Theilen, Heather Campbell, Erica Johnstone, Meredith Humphreys, Sunni Mumford, Alexandra Purdue-Smithe, Lindsey Sjaarda, Neil Perkins, Robert Silver, Enrique Schisterman

 

11:00 a.m. - 11:15 a.m.

 

O-090: The Association between Living in a Food Desert and the Likelihood of Initiating Breastfeeding
Adriana Campos, Jean Paul Tanner, Ronee E Wilson, Jason L Salemi, Peeraya Sawangkum, Kimberly Fryer, Adetola Louis-Jacques

 

11:15 a.m. - 11:30 a.m.

 

O-091: How Late Is Too Late to Reverse the Effects of the Developmental Origins of Health and Disease?
Craig E Pennell, Carol A Wang, Wendy H Oddy, Claire E Meyerkort, Stephen G Matthews

 

11:30 a.m. - 11:45 a.m.

 

O-092: Predictors of Teenage Pregnancy in Zambia between 2007 and 2018
Claire H Packer,  Nelly-Claire Muntalima, Ana M Langer, Michael T Mbizvo

 

Development Programming II
Moderators: 
TBD

Room Coming Soon

10:15 a.m. - 10:30 a.m.

 

O-093: Maternal Exposure to Δ9-Tetrahydrocannabinol Results in Symmetrical IUGR Associated with Cardiac Dysfunction in Postnatal Life
Kendrick Lee, Kristian McCarthy, Steven R Laviolette, Qingping Feng, Daniel B Hardy

 

10:30 a.m. - 10:45 a.m.

 

O-094: Under-Expression of Placental Endocrine-Specific Igf2 Programmes Cardiovascular Disease in the Adult Male Offspring
W Ching, Y Niu, T A Garrud, H Yong, E R Christoforou, J Lopez-Tello, D A Giussani, A N Sferruzzi-Perri

 

 

10:45 a.m. - 11:00 a.m.

 

O-095: Accumulation of Suboptimal Periconceptional Social, Lifestyle and Medical Exposures as Markers for the Maternal Vulnerable Condition and Impairment of Embryonic Growth: The Rotterdam Periconceptional Cohort (Predict Study)
Sofie KM van Zundert, Lenie van Rossem, Sten P Willemsen, Lindsey van der Meer, Hiske E Ernst-Smelt, Régine PM Steegers-Theunissen

 

11:00 a.m. - 11:15 a.m.

 

O-096: Maladaptive Cardiomyocyte Calcium Handling in Adult Offspring of Hypoxic Pregnancy: Protection by Antenatal Maternal Melatonin
Mitchell C Lock, Kerri LM Smith, Youguo Niu, Olga V Patey, Sage G Ford, Andrew W Trafford, Dino A Giussani, Gina LJ Galli

 

11:15 a.m. - 11:30 a.m.

 

O-097: Vascular Disorders of Pregnancy Increase Susceptibility to Neonatal and Infantile Pulmonary Hypertension in High-Altitude Populations
Alexandra Heath,  Colleen G Julian, Lilian Toledo-Jaldin, Inge von Alvensleben, Litzi Lazo Vega, Hussna Yasini, Jesus Dorado Madera, Margaret Stalker, Julie A Houck, Lorna G Moore

 

11:30 a.m. - 11:45 a.m.

 

O-098: Reduced TGFβ Responsiveness in Skeletal Muscle Satellite Cells from Lambs with Fetal Growth Restriction
Rosa I Luna Ramirez, Miranda J Anderson, Ravi Goyal, Sean W Limesand

 

Reproductive Biology II
Moderators: 
TBD

Room Coming Soon

10:15 a.m. - 10:30 a.m.

 

O-099: Polycomb Repressive Complex 2 Antagonizes Wound Healing Responses in the Decidual Stroma by Modulating the Transforming Growth Factor Beta Pathway
Ivan Osokine, Damon Rideaux, Tara McIntyre, Johan Siewiera, Adrian Erlebacher

 

10:30 a.m. - 10:45 a.m.

 

O-100: Proteomic Analysis of Extracellular Vesicles Secreted by Primary Endometrial Epithelial Cells from Fertile Women Reveals Functions Related to Embryo Implantation Not Present in an Endometrial Epithelial Cell Line
Marina Segura-Benítez, María Cristina Carbajo-García, Ana Corachán, Amparo Faus, Antonio Pellicer, Hortensia Ferrero

 

10:45 a.m. - 11:00 a.m.

 

O-101: Jagged1 Regulates Endometrial Receptivity in Both Humans and Mice
Wei Zhou, Ellen Menkhorst, Evdokia Dimitriadis

 

11:00 a.m. - 11:15 a.m.

 

O-102: Antiphospholipid Antibodies Accelerate Endometrial Stromal Cell Decidualization and Senescence and Induce Inflammation via TLR4, p38 MAPK and ROS Signaling
Mancy Tong, Teimur Kayani, Deidre M Jones, Lawrence W Chamley, Vikki M Abrahams

 

11:15 a.m. - 11:30 a.m..

 

O-103: The Long-Term Impact of Selective Progesterone Receptor Modulator (SPRM) Ulipristal Acetate (UPA) on the Cell Cycle and Cell Proliferation in Human Endometrium as Assessed by RNA Sequencing
Aleksandra Tsolova, Rohan Chodankar, Alison Murray, Lucy Whitaker, Moira Nicol, Alistair Williams, Hilary Critchley

 

11:30 a.m. - 11:45 a.m.

 

O-104: Next Generation of Human Endometrial Organoids: Bioengineering-Based Strategies for Preserving Tissue-Specific Extracellular Environment
Emilio Francés-Herrero, Elena Juárez-Barber, Hannes Campo, Sara López-Martínez, Lucía de Miguel-Gómez, Amparo Faus, Antonio Pellicer, Hortensia Ferrero, Irene Cervelló

 
 

Placenta II
Moderators: 
TBD

Room Coming Soon

10:15 a.m. - 10:30 a.m.

 

O-105: Fibronectin-Integrin Interactions Regulate Placental Endothelial Cell Migration in Severe Fetal Growth Restriction
Diane L Gumina, Shuhan Ji, Kathryn McPeak, Emily J Su

 

10:30 a.m. - 10:45 a.m.

 

O-106: Characterization of Regulation of NLRP3 Inflammasome Activity in Placental Hofbauer Cells
Magnolia G Wang, Seth Guller

 

10:45 a.m. - 11:00 a.m.

 

O-107: AKT Signaling Controls Trophoblast Development and Placentation
Keisuke Kozai, Mae-Lan Winchester, Mikaela E Simon, Khursheed Iqbal, Masanaga Muto, Regan L Scott, Chad Slawson, Michael J Soares

 

11:00 a.m. - 11:15 a.m.

 

O-108: Changes in Lipid Profiles of Placental Exosomes in Maternal Plasma Characterize Pregnancies with a Small-for-Gestational Age Fetus
Miira M Klemetti, Ante BV Pettersson, Porter R Tyler, Aafaque Khan, Premy Shan, Hannes Röst, Martin Post, Isabella Caniggia

 

11:15 a.m. - 11:30 a.m.

 

O-109: Velocity-Selective Arterial Spin Labeling Perfusion Measurements in 2nd Trimester Human Placenta
Daniel Seiter, Ruiming Chen, Kai Ludwig, Ante Zhu, Dinesh Shah, Sean Fain, Oliver Wieben, Kevin M Johnson

 

11:30 a.m. - 11:45 a.m.

 

O-110: Placental NRF2 May Serve a Key Role in Maternal-Fetal Tolerance during Pregnancy
Kyunghee Hong, Youn-Tae Kwak, Sribalasubashini Muralimanoharan, Carole R Mendelson

 

Reproductive Endocrinology and Infertility II
Moderators: 
TBD

Room Coming Soon

10:15 a.m. - 10:30 a.m.

 

O-111: Premenstrual Dysphoric Disorder (PMDD) Is Associated with Estradiol-Dependent Aberrations in Cellular Ca2+ Homeostasis and the Endoplasmic Reticulum Stress Response
Howard Li, Neelima Dubey, Jessica F Hoffman, David R Rubinow, Peter J Schmidt, David Goldman

 

10:30 a.m. - 10:45 a.m.

 

O-112: Examination of Androgen Effects on Female Reproductive Axis: Hypothalamus-Pituitary-Ovary
Sheng Wu, Olubusayo Awe, Mingxiao Feng, James Segars

 

10:45 a.m. - 11:00 a.m.

 

O-113: Disparities in Seeking Infertility Care: Data from the 2017-2019 CDC National Survey of Family Growth
Lauren E Barrison, Allison R Kumnick, Veronica Gomez-Lobo, Jaqueline Y Maher

 

11:00 a.m. - 11:15 a.m.

 

O-114: Normal Weight Women with Polycystic Ovary Syndrome (PCOS) Exhibit Oxidative Stress in Response to Saturated Fat Ingestion Even in the Absence of Abdominal Adiposity (AA)
Frank González, Robert V Considine, Ola A Abdelhadi, Jiaping Xue, Anthony J Acton

 

11:15 a.m. - 11:30 a.m.

 

Speaker Information Coming Soon!

 

11:30 a.m. - 11:45 a.m.

 

Speaker Information Coming Soon!

 

Clinical and Translational Perinatology II
Moderators: 
TBD

Room Coming Soon

10:15 a.m. - 10:30 a.m.

 

O-115: Preferred Timing of Efficacy of a New Therapeutic Candidate, Rytvela, for Prevention of Inflammation-Induced Preterm Birth and Fetal Growth Restriction
Sarah-Eve Loiselle, Renay Poupart, Xin Hou, Mathieu Nadeau-Vallée, France Côté, Tiffany Habelrih, Christiane Quiniou, Sylvain Chemtob

 

10:30 a.m. - 10:45 a.m.

 

O-116: Comparative Adverse Effects of Antenatal Glucocorticoid Formulations: Studies in the Chicken Embryo
T A Garrud, N Teulings, F G Conlon, W Tong, S G Ford, Y Niu, L M Nicholas, J B Derks, S E Ozanne, D A Giussani

 

10:45 a.m. - 11:00 a.m.

 

O-117: Maternal Leukocyte DNA Methylation during Asymptomatic Pregnancy and Future Spontaneous Preterm Birth among Black American Women
Shannon Gillespie, Chenggong Han, Zilu Liu, Cindy Anderson, Shili Lin

 

11:00 a.m. - 11:15 a.m.

 

O-118: Impact of Progesterone on Mechanism of Preterm Premature Rupture of Membrane
Heejoong Lee, Banghyun Lee

 

11:15 a.m. - 11:30 a.m.

 

O-119: A Novel Murine Model of Cytomegalovirus Infection in Pregnancy
Angela Shaddeau, Gregory Kirschen, Anna Chudnovets, Quan Na, Ayan Ghosh, Halli Miller, Jun Lei, Ravit Boger, Andrew Thagard, Karen Racicot, Irina Burd

 

11:30 a.m. - 11:45 a.m.

 

O-120: Psychological Distress during Pregnancy and Adverse Maternal and Perinatal Health Outcomes; the Role of Socioeconomic Status
Leonie A Daalderop, Jacqueline Lagendijk, Eric AP Steegers, Hanan El Marroun, Anke G Posthumus

 

12:00 p.m. - 1:00 p.m. 

Diversity, Equity and Inclusion Forum
*Boxed lunches will be provided at no cost for this session. The capacity for this session is 100 attendees and registration for this session will close once full or on the Registration Deadline.

Room Coming Soon

Moderator: 
Ayman Al-Hendy, MD, PhD

 

How to Create an Environment Supportive of Diversity, Equity and Inclusion
Genevieve S. Neal-Perry, MD, PhD, Chief, Reproductive Endocrinology and Infertility
University of Washington, Seattle, WA, USA

 

12:00 p.m. - 1:00 p.m.

Lunch and Learn Symposium III 
*Boxed lunches are available and complimentary through the Registration Deadline only.

 
 

Don't Get Lost in Translation: Importance of In Vivo and In Vitro Model Validation
Supported by Bayer
Moderators: 

Irene Cervello, PhD

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12:00 p.m. - 12:25 p.m.

 

Back-Translation of Clinical Endpoints and Model Validation in Preclinical Research (fibroids examples)
Thomas M. Zollner, MD

 

12:25 p.m. - 12:50 p.m.

 

Modeling Artificial Ovary 
Monica M. Laronda, PhD

 

12:50 p.m. - 1:00 p.m.

 

Session Q&A

 
12:00 p.m. - 1:00 p.m.

Lunch and Learn Symposium IV
*Boxed lunches are available and complimentary through the Registration Deadline only.

 

 

Beyond Surgery: Managing Uterine Fibroids in 2021..and Beyond

Supported by Myovant
Moderators: 
Shannon Whirledge, PhD, MHS
Bill Catherino, MD, PhD

Room Coming Soon

12:00 p.m. - 12:15 p.m

 

Non-Surgical Interventions for Uterine Fibroids
Elizabeth A. Stewart, MD

 

12:15 p.m. - 12:30 p.m.

 

Non-Hormonal Options for Uterine Fibroids
Mostafa Borahay, MBBCh, MSc, PhD

 

12:30 p.m. - 12:45 p.m

 

Hormonal Options for Uterine Fibroids
Ayman Al-Hendy, MD, PhD

 

12:45 p.m. - 1:00 p.m.

 

Session Q&A

 

1:15 p.m. - 2:45 p.m.

Concurrent Oral Presentations IV

 

Fetus II
Moderators: 
TBD

Room Coming Soon

1:15 p.m. - 1:30 p.m.

 

O-121: MAP4K4: Identification of a Novel Candidate Gene Using Prenatal Exome Sequencing Data and Functional Modeling in Zebrafish
Neeta L Vora, John Griffin, Kelly Gilmore, Julie K Holsclaw, Elizabeth Bhoj, Erica E Davis

 

1:30 p.m. - 1:45 p.m.

 

O-122: An Aberrant Endothelial Cell Response to Flow: Mechanistic Implications for Congenital Heart Defects in the Feto-Placental Unit
Yalda Afshar, Anhyo Jeong, Christine Jang, Gary Satou, Mark Sklansky, M Luisa Iruela-Arispe

 

1:45 p.m. - 2:00 p.m.

 

O-123: Measuring In Vivo Arterial Stiffness in Fetal Life
Nima Moghaddas, Beth J Allison, Youguo Niu, Kimberley J Botting, Carmel M McEniery, Dino A Giussani

 

2:00 p.m. - 2:15 p.m.

 

O-124: In Utero e-Cigarettes Exposure Enhances Neonatal Brain Ischemic Damage: Role of the miRNA-30c
Andrew Walayat, Yanyan Zhang, Yong Li, Asanjan Hosseini Maryam, Daliao Xiao

 

2:15 p.m. - 2:30 p.m.

 

O-125: Early and Mid-Gestation Zika Virus (Zikv) Infection in the Olive Baboon (Papio anubis) Leads to Neurological Birth Defects Due to Congenital Zika Syndrome (czs)
Sunam G Dockins, Darlene N Reuter, Marta E Maxted, Ashley A Martin, Molly E Dubois, James F Papin, Dean A Myers

 

2:30 p.m. - 2:45 p.m.

 

O-126: Thyroid Hormone Dominates IGF1 Expression and Actions in Fetal Cardiomyocytes
Natasha N Chattergoon, Samantha Louey, Sonnet Jonker, George Giraud, Kent L Thornburg

 

Parturition III
Moderators: 
TBD

Room Coming Soon

1:15 p.m. - 1:30 p.m.

 

O-127: Black and White Women in the United States Military Have Comparable Rates of Preeclampsia and Post-Preeclamptic Cardiovascular Disease
Andrea I Loewendorf, Emily A Stone, Lee Ann Zarzabal, Thornton Mu, Amelia Duran-Stanton

 

1:30 p.m. - 1:45 p.m.

 

O-128: Racial and Ethnic Disparities in Complications among Patients Undergoing a Trial of Labor after Cesarean Section at Mount Sinai Hospital
Ayisha Brielle Buckley, Stephanie Sestito, Tonia Ogundipe, Natalie Cohen, Mitchell Rosenberg, Kelly Wang, Jill Berkin, Stoffels Guillaume, Chelsea DeBolt, Jessica Peterson, Joanne Stone, Angela Bianco, Luciana Vieira

 

 

1:45 p.m. - 2:00 p.m.

 

O-129: Potential Risk of Infection of First Trimester Placentas by SARS-CoV2
Sampada Kallol, Laura Martin-Sancho, Donald Pizzo, Sumit K Chanda, Mana Parast, Francesca Soncin

 

2:00 p.m. - 2:15 p.m.

 

O-130: Impact of SARS-CoV-2 Infection during Pregnancy by Maternal Race-Ethnicity
Darios Getahun, Lawrence D Lurvey, David Braun, David A Sacks, Jiaxiao Shi, Vicki Y Chiu, Morgan R Peltier, Michael J Fassett

 

2:15 p.m. - 2:30 p.m.

 

O-131: Stressors in Fertility Treatment: The Impact of the COVID-19 Pandemic
Sarah Dynia, Caroline Peschansky, Safina Usmani, Sonia Patel, Kayla Vitale, Jawaria Amir, Royi Lynn, Lauren Grimm, Erica Louden, Roohi Jeelani, Angie Beltsos

 

2:30 p.m. - 2:45 p.m.

 

O-132: Expression of SARS-CoV-2 Entry Molecules at Maternal-Fetal Interface and Regulation of Proinflammatory Cytokines and Coagulation Factor III in Human Placental Microvascular Endothelial Cell by Spike Protein
Xiaofang Guo, Umit A Kayisli, Asli Ozmen, Nihan Semerci, Kellie Larsen, Zhi Tian, Frederick Schatz, Diane Allen-Gipson, Ozlem Guzeloglu-Kayisli, Charles J Lockwood

 

Placenta III
Moderators: 
TBD

Room Coming Soon

1:15 p.m. - 1:30 p.m.

 

O-137: Chorionic Somatomammotropin RNA Interference Reduces Global Nutrient Uptake and Umbilical Blood Flow Resulting in Intrauterine Growth Restriction
Amelia R Tanner, Cameron S Lynch, Victoria C Kennedy, Asghar Ali, Quinton A Winger, Paul J Rozance, Russell V Anthony

 

1:30 p.m. - 1:45 p.m.

 

O-138: Trophoblast-Specific Knockdown of the System A Amino Acid Transporter, Slc38a2/SNAT2, Causes Fetal Growth Restriction in Mice
Owen R Vaughan, Elena Silva, Kenneth Barentsen, Russell V Anthony, Thomas L Brown, Theresa L Powell, Thomas Jansson

 

1:45 p.m. - 2:00 p.m.

 

O-139: An In Vitro Placenta Model with a Native Stroma for Mechanistic Transport Studies
Katherine M Nelson, Sarah A Geissler, Jason P Gleghorn

 

2:00 p.m. - 2:15 p.m.

 

O-140: Obesity Downregulates Lipid Metabolism Genes in First Trimester Placenta
Aisha Rasool, Begum Aydogan Mathyk, Danielle Roncari, Perrie O'Tierney-Ginn

 

2:15 p.m. - 2:30 p.m.

 

Speaker Information Coming Soon!

 

2:30 p.m. - 2:45 p.m.

 

Speaker Information Coming Soon!

 
 

Reproductive Biology III
Moderators: 
TBD

Room Coming Soon

1:15 p.m. - 1:30 p.m.

 

O-137: Thymic Progesterone Receptor Expression Regulates Maternal Thymic Involution in Murine Pregnancy
Soo Hyun Ahn, Sean L Nguyen, Tae-Hoon Kim, Jae-Wook Jeong, Ripla Arora, Margaret G Petroff

 

1:30 p.m. - 1:45 p.m.

 

O-138: A Role for the IL-33-ILC2 Axis in Driving Uterus-Intrinsic Parturition Pathways in Mice
Johan Siewiera, Madelene Dahlgren, Kelly Cautivo, Damon Rideaux, Ari Molofsky, Adrian Erlebacher

 

1:45 p.m. - 2:00 p.m.

 

O-139: Single-Cell RNA Sequencing Identifies Novel Uterine Macrophage Population Increased by Regulatory T Cells and Associated with Decreased Fetal Loss
Emma L Lewis, Paige M Porrett, Michal A Elovitz

 

2:00 p.m. - 2:15 p.m.

 

O-140: Pluripotent Stem Cell Derived Endometrial Stromal Fibroblasts Co-Culture with Endometrial Epithelial Organoids to Form a 3-Dimensional Model of the Human Endometrium
Virginia Chu Cheung, Chian-yu Peng, Mirna Marinic, Noboru J Sakabe, Ivy Aneas, Vincent J Lynch, Carole Ober, Marcelo A Nobrega, John A Kessler

 

2:15 p.m. - 2:30 p.m.

 

O-141: The Vertical Transfer of Maternal Immune Cells during Pregnancy Promotes Neonatal Immunity against Viral Infections in Mice
Ina Stelzer, Christopher Urbschat, Kristin Thiele, Ioanna Triviai, Julian Kottlau, Felix Stahl, Maria Emilia Solano, Petra Arck

 

2:30 p.m. - 2:45 p.m.

 

O-142: Differentiation of Mouse iPSCs into Functional Oocytes
Raymond M Anchan, Nicholas W Ng, Kha U Dam, Ankrish Milne, Emily R Disler, Nicole Dunn, Kevin M Elias, Elizabeth Ginsburg

 

Preeclampsia II
Moderators: 
TBD

Room Coming Soon

1:15 p.m. - 1:30 p.m.

 

O-143: HO-1 Genetic Variants Display Racial Diversity and May Impact Hypertensive Disorders in Pregnancy
Tianyanxin Sun, Nima Mousavi, Ronald J Wong, Nazish Sayed, Joseph C Wu, David K Stevenson, Melissa Gymrek, Virginia D Winn

 

1:30 p.m. - 1:45 p.m.

 

O-144: Surgically Increasing Uteroplacental Impedance Results in Attenuated Uterine Vascular Remodeling and Preeclampsia-Related Placental Secretomics during Pregnancy
Nga Ling Ko, Narmin Mukhtarova, Catrina Hood, Ying Wai Lam, George Osol

 

1:45 p.m. - 2:00 p.m.

 

O-145: The New Generation Antiplatelet Agent Prasugrel Represents an Exciting Novel Candidate Therapy for Preeclampsia
Natalie Hannan, Natasha De Alwis, Natalie Binder, Sally Beard, Vi Nguyen, Kaitu'u-Lino Tu'uhevaha, Stephen Tong

 

2:00 p.m. - 2:15 p.m.

 

O-146: Sildenafil Improves Placental Function and Remodeling in Preeclamptic Rats
Dylan J Lawrence, Carolyn L Bayer

 

2:15 p.m. - 2:30 p.m.

 

O-147: Differential Distribution of Tryptophan-Metabolites in Fetal and Maternal Circulations during Pregnancy: Preeclampsia-Elevated Aryl Hydrocarbon Receptor Ligands
Ying-jie Zhao, Chi Zhou, Ying-ying Wei, Hui-hui Li, Kai Wang,  Jing Zheng

 

2:30 p.m. - 2:45 p.m.

 

O-148: Can WS1442 Ameliorate Maternal Vascular Dysfunction in Preeclampsia?
Stephanie A Worton, Yasmin Mills, Susan L Greenwood, Jenny E Myers

 

Gynecology Oncology
Moderators: 
TBD

Room Coming Soon

1:15 p.m. - 1:30 p.m.

 

O-149: Evaluation of ATR Inhibitors for Targeted Therapy of Ovarian Clear Cell Carcinoma
Jing Ji,  Gloria Huang, Jing Ji, Zhigui Li, Emily Sherman, Oloruntoba Osagie, Shijun Mi, Whitney Soble, Jessie Li

 

1:30 p.m. - 1:45 p.m.

 

O-150: Endoplasmic Reticulum Stress Response to Hyperinsulinemia in Endometrial Epithelial Cells Depends on PIK3CA Mutation
Mike R Wilson, Ronald L Chandler

 

1:45 p.m. - 2:00 p.m.

 

O-151: ACS NSQIP - Personalised Risk Prediction Tool for Postoperative Complications in Gynaeoncology Surgery?
Lusine Sevinyan, Sadie Jones, Jonathan Horne, Rasiah Bharathan, Anil Tailor, Simon Butler-Manuel, Peter Williams, Thumuluru Kavitha Madhuri

 

2:00 p.m. - 2:15 p.m.

 

Speaker Information Coming Soon!

 

2:15 p.m. - 2:30 p.m.

 

Speaker Information Coming Soon!

 

2:30 p.m. - 2:45 p.m.

 

Speaker Information Coming Soon!

 

2:45 p.m. - 4:15 p.m. 

Poster Session II

Room Coming Soon

4:15 p.m. - 6:15 p.m.

Mini Symposia II

 

SRI – SSR Joint Session: Immune Cell Regulation of Implantation/Pregnancy
Moderator: 
Bo Rueda, PhD
Soo Hyun Ahn

Room Coming Soon

4:15 p.m. - 4:40 p.m.

 

Neutrophils at the Maternal-Fetal Interface: Friend or Foe?
Vicki M. Abrahams, PhD

 

4:40 p.m. - 5:05 p.m.

 

The Stage Is Set Before the Play Commences – Maternal Immunological Detection of the Conceptus
Troy Ott, PhD

 

5:05 p.m. - 5:30 p.m.

 

Maternal Immunity and Tolerance During Pregnancy
Margaret G. Petroff, PhD

 

5:30 p.m. - 5:55 p.m.

 

Fetal-Maternal Disagreement: Immune Responses in Placental Villitis
Elizabeth Ann Enninga, PhD

 

5:55 p.m. 6:15 p.m.

 

Session Q&A

 

Update on Diagnostics and Therapeutics for Preterm Birth
Moderators: 
David M. Olson, PhD
Kelycia B. Leimert, PhD

Room Coming Soon

4:15 p.m. - 4:25 p.m.

 

Overview of the Pathway to Preterm Birth
Kelycia B. Leimert, PhD

 

4:25 p.m. - 4:45 p.m.

 

The Need for, Barriers to, and Hope for New Preterm Birth Diagnostics and Therapeutics
David M. Olson, PhD

 

4:45 p.m. - 5:10 p.m.

 

New and Emerging Biomarker Prediction Tests for Preterm Birth
Laura Jelliffe-Pawlowski, PhD

 

5:10 p.m. - 5:35 p.m.

 

Development of Novel Therapeutics to Counter Preterm Birth
Sylvain Chemtob, MD, PhD

 

5:35 p.m. - 6:00 p.m.

 

Title Coming Soon
Elizabeth (Beth) Garnder, CMO

 

6:00 p.m. - 6:15 p.m.

 

Session Q&A

 

Drivers and Therapeutic Targets for Gynecologic Cancers Associated with Benign Gynecologic Conditions
Moderators: 
Dineo Khabele, MD, FACOG, FACS
Gloria Huang, MD

Room Coming Soon

4:15 p.m. - 4:40 p.m.

 

ARID1A as a Driver and Target for Therapy for Endometriosis-Associated Ovarian Cancer (Implications for Immunotherapy)
Rugang Zhang, PhD

 

4:40 p.m. - 5:05 p.m.

 

Toxicant Exposure, Endocrine Disruptors and Adenomyosis (Environmental Influence)
Kaylon L. Bruner-Tran, PhD

 

5:05 p.m. - 5:30 p.m.

 

The Insulin/Insulin Growth Factor and Sex Hormone Axes in the Normal Endometrium and in Tumor Microenvironment of Endometrial Cancer (Environmental Influence of Obesity and Implications for Immunotherapy)
Gloria Huang, MD

 

5:30 p.m. - 5:55 p.m.

 

Mouse Models of Endometriosis-Associated Gynecologic Cancers
Warren B. Nothnick, PhD

 

5:55 p.m. - 6:15 p.m.

 

Session Q&A

 

Antenatal Steroid Therapy Optimisation. From Clinic to Bench and Back Again
Moderators: 
Matthew W. Kemp, PhD

Cynthia Gyamfi-Bannerman, MD, MSc

Room Coming Soon

4:15 p.m. - 4:40 p.m.

 

When, What and How Often? Revisiting the Scientific Basis of Antenatal Steroid Therapy
Citra N. Mattar, PhD, MBBS, Mmed, MRANZCOG

 

4:40 p.m. - 5:05 p.m.

 

Hunting for Goldilocks - Efforts Past and Present to get Antenatal Steroid Dosing Just Right
Matthew W. Kemp, PhD

 

5:05 p.m. - 5:30 p.m.

 

Optimisation of Antenatal Steroids for Low and Middle Income Countries
Alan H Jobe, MD, PhD

 

5:30 p.m. - 5:55 p.m.

 

Short & Long Term Benefits & Risks of Multiple Courses of Antenatal Corticosteroids
Kellie E. Murphy MD, MSc

 

5:55 p.m. 6:15 p.m.

 

Session Q&A

 

Role of miRNA’s and Inflammation in the Pathology of Endometriosis
Moderators: 
Niraj Joshi
Valerie A. Flores, MD

Room Coming Soon

4:15 p.m. - 4:40 p.m..

 

Insights Into Contributions of Stem Cell and Inflammatory Pathways in the Pathophysiology of Endometriosis
Valerie A. Flores, MD

 

4:40 p.m. - 5:05 p.m..

 

Macrophages in the Pathophysiology of Endometriosis: Mouse Models As Tools for Clinical Translation
Erin Greaves, PhD

 

5:05 p.m. - 5:30 p.m.

 

miRNA’s in Endometriosis: Pathological Insights and Clinical Implications From a Baboon Model
Asgerally T. Fazleabas, PhD

 

5:30 p.m. - 5:55 p.m.

 

miRNA’s in Endometriosis: Diagnostic Potential and Pathophysiology in Women With Disease
Hugh S. Taylor, MD

 

5:55 p.m. 6:15 p.m.

 

Session Q&A

 

An Update on the Impact of COVID-19 on Maternal-Child Health,
Supported by March of Dimes
Moderators: 
Rahul Gupta
David M. Aronoff, MD

 

Room Coming Soon

4:15 p.m. - 4:40 p.m.

 

Risks to the fetus of maternal COVID-19, an evidence-based analysis
Andrea Edlow, MD

 

4:40 p.m. - 5:05 p.m.

 

Insights into SARS-CoV-2 pathogenesis during pregnancy from humans and non-human primate models of infection
Kristina Adams Waldorf, MD

 

5:05 p.m. - 5:30 p.m.

 

Placental changes in response to infection and vaccination
Jeff Goldstein, MD, PhD

 

5:30 p.m. - 5:55 p.m.

 

What COVID-19 may mean to the developmental origins of health and disease
Rebecca Simmons, MD

 
 

5:55 p.m. 6:15 p.m.

 

Session Q&A

 

9:00 a.m. - 1:00 p.m.

Career Development Workshops

Virtual

1:30 p.m. - 2:30 p.m.

Your Grant in One Page Clinic

Virtual