Detailed Program

7:00 a.m. - 6:00 p.m.

Registration

Level II Mezzanine

8:30 a.m. - 5:00 p.m.

Fetal Physiology Satellite

101

Placenta Satellite

102

Endometrial Satellite

103

Ovarian Biology Satellite

104

Preterm Birth International Collaborative (PREBIC) Satellite

209

Myometrium and Parturition Satellite

208

5:15 p.m. - 6:15 p.m.

208

Paige Cooper, PhD
Program Officer
Burroughs Wellcome Fund

Idhaliz Flores, PhD
Professor
Ponce Health Sciences University - Ponce Research Institute

Carlos Simon, MD, PhD
Professor
Carlos Simon Foundation

Shruthi Mahalingaiah, MD, MS
Associate Professor
Harvard University
Massachusetts General Hospital

6:30 p.m. - 8:00 p.m.

Terrace (Level II)

7:00 a.m. - 6:00 p.m.

Registration

Level II Mezzanine

8:00 a.m. - 8:10 a.m.

Irina Burd, MD PhD

Ballroom A

8:10 a.m. - 9:00 a.m.

Translational lessons for the development of effective immunotherapies
George Coukos, MD, PhD

Ballroom A

9:00 a.m. - 10:00 a.m.

Ballroom A

9:00 a.m. - 9:15 a.m.

O-001: Placental-Specific ER Stress Disturbs Maternal Cardiometabolic Adaptations to Pregnancy in a Murine Model of Fetal Growth Restriction Near Term
Rachael Crew, Noa Hasky, Chen Zhang, Sophie Dargan, Anna Cochrane, Shintaro Maki, Miguel Constancia, Susan Ozanne, Dino Giussani, D. Stephen Charnock-Jones, Hong Wa Yung

9:15 a.m. - 9:30 a.m.

O-002: Relationship Between Time-in-Range, Hemoglobin A1c, and Adverse Neonatal Outcomes in Patients with Diabetes in Pregnancy
Jillian Jetmore, Katherine Pepper, Salimah Gangji, Erkan Kalafat, Rebecca Horgan, Jerri Waller, George Saade, Marwan Ma'ayeh

9:30 a.m. - 9:45 a.m.

O-003: M2-polarized Macrophages are Linked to the Aberrant Profibrotic Tissue Response of the Postpartum Uterus to Trauma in a Mouse Model of Uterine Injury
Maria Chaves Rivera, Sydney Bell, Abigail Solomon, Jialyu Huang, Ruiqi Li, Harvey Kliman, Aya Tal, Yuval Kluger, Reshef Tal

9:45 a.m. - 10:00 a.m.

O-004: Genistein and Pioglitazone as Promising Repurposed Drugs to Treat Endometrial Failure Independent of Endometrial Timing
Antonio Parraga-Leo, Patricia Sebastian-Leon, Francisco José Sanz, Josefa Sanchez-Reyes, María del Carmen Vidal, Imma Sanchez-Ribas, Antonio Pellicer, Marina Sirota, Patricia Diaz-Gimeno

10:00 a.m. - 12:00 p.m.

Hall A

12:00 p.m. - 1:00 p.m.

208

Objective: To help emerging reproductive scientists discover, articulate, and effectively communicate their professional purpose, connecting their personal values and scientific/clinical goals to broader impacts in reproductive health. 

In this interactive session, participants will learn strategies to align their personal values with their research and career trajectory and to communicate this purpose clearly and authentically in professional settings. Participants will leave this workshop with a personalized prompt card that reinforces their research purpose and renewed confidence to clearly communicate this in interviews, networking, and advocacy settings.

From Patient to Purpose: Turning a Health Odyssey into a Clear Research Why
Kaela Varberg, PhD
Independent Investigator, Neonatology - Children’s Mercy Research Institute (CMRI)
Rare Disease Patient and Advocate, Reproductive Scientist, and SRI Career Development Committee Member

12:00 p.m. - 1:00 p.m.

209

This interactive session will explore how academic departments and researchers can engage effectively
in development and philanthropic activities to advance their programs and institutional missions.
Panelists will share practical strategies for identifying funding sources, cultivating donor relationships,
aligning philanthropic goals with academic priorities, and leveraging philanthropy to build sustainable
initiatives in reproductive sciences. Participants will gain insights into successful partnerships with
development offices and learn how to articulate their vision in ways that inspire meaningful support.

Moderators:
Hilary Critchley, MD, DSc, FRCOG
Hugh Taylor, MD

Panelists:

Dee E. Fenner, MD
Bates Professor of Diseases of Women and Children
Chair, Department of Obstetrics and Gynecology
University of Michigan

Amy Murtha, MD
Dean
Rutgers Robert Wood Johnson Medical School

Jonathan Cherry
Senior Director, Research Operations
March of Dimes

1:15 p.m. - 3:15 p.m.

Precision Medicine Drives Regeneration in Obstetrics and Gynecology 

Sponsored by Carlos Simon Foundation

Moderators:
Aymara Mas Perucho, PhD
Moderator II

101

1:15 p.m. - 1:45 p.m.

Precision Medicine Drives Innovative Regenerative Treatments for Infertility
Kathleen O'Neill, MD
University of Pennsylvania  

1:45 p.m. - 2:15 p.m.

Harnessing vaginal inflammation and microbiome: a machine learning model for predicting IVF success
Caroline Mitchell, MD, MPH
Massachusetts General Hospital - Vincent Center for Reproductive Biology

2:15 p.m. - 2:45 p.m.

Molecular landscape underlying endometrial decidualization resistance
Tamara Garrido-Gomez, PhD
Fundacion Carlos Simon-INCLIVA Health Research Institute

2:45 p.m. - 3:15 p.m.

Single-Cell Analysis Provides New Insights into Cervical Function
Mala Mahendroo, PhD
UT Southwestern Medical Center

Senescence and Renewal in Reproductive and Lower Urinary Tracts 

Moderators:
Kathleen Connell, MD - University of Colorado Anschutz
Moderator II

102

1:15 p.m. - 1:45 p.m.

Chimerism  as the basis of Organ Repair: CDX2 Cells in Pregnancy and Cardiovascular Regeneration
Sangeetha Vadakke-Madathil, PhD
Icahn School of Medicine at Mount Sinai

1:45 p.m. - 2:15 p.m.

Leveraging Senolytics for Pelvic Floor Renewal
Maria Florian-Rodriguez, MD
UT Southwestern Medical Center

2:15 p.m. - 2:45 p.m.

The role of cellular senescence in ovarian aging
Augusto Schneider, PhD
Universidade Federal de Pelotas

2:45 p.m. - 3:15 p.m.

Effect of Urothelial and Immuno-senescence on Lower Urinary Tract Function: implications for women's health
Indira Mysorekar, PhD
Baylor College of Medicine

From Inflammation to Regeneration: Sugar Structures at the Frontlines of Reproductive Biology

Sponsored by University of North Carolina Chapel Hill

Moderators:
Amanda Lewis, PhD
Moderator II

103

1:15 p.m. - 1:45 p.m.

The Molecular Dialogue between Glyco- and Repro- Biology
Anne Dell, PhD
Imperial College

1:45 p.m. - 2:15 p.m.

Urinary Glycosaminoglycans: Important Players in Pathophysiology of Recurrent Urinary Tract Infections 
Nicole De Nisco, PhD
The University of Texas at Dallas

2:15 p.m. - 2:45 p.m.

The role of glycans in shaping microbiota-host interactions and preterm birth risk phenotypes
David MacIntyre, PhD
Robinson Research Institute, Adelaide University

2:45 p.m. - 3:15 p.m.

The Impact of Aberrant Glycosylation on Gynecologic Pathology
Susan Bellis, PhD
The University of Alabama at Birmingham

Shared Biology Between Benign and Malignant Conditions in Reproductive Health

Moderators:
Warren Nothnick, PhD
Moderator II

104

1:15 p.m. - 1:45 p.m.

Ovarian tubal stroma in benign and malignant tumors
Lan Coffman, MD, PhD
University of Pittsburgh - Magee Women's Research Institute

1:45 p.m. - 2:15 p.m.

Progesterone Resistance in Endometriosis and Endometrial Cancer
Tae Hoon Kim, PhD
University of Missouri

2:15 p.m. - 2:45 p.m.

Immune checkpoint action in normal cells and cells of benign and malignant diseases of the adnexa
Joshua Johnson, PhD
University of Colorado Anschutz

2:45 p.m. - 3:15 p.m.

Gestational Trophoblastic Disease: Insights Into Trophoblast Biology
Rima Slim, PhD
McGill University Health Centre

3:15 p.m. - 3:30 p.m.

Level I Foyer

3:30 p.m. - 5:30 p.m.

101

3:30 p.m. - 3:45 p.m.

President's Presenter Award
O-005: MiR-21-5p Rescues Peripheral Vascular Dysfunction in Embryos Exposed to Developmental Hypoxia
Aaliyah Razi, Anna Cochrane, Youguo Niu, Sage Ford, Rachael Crew, German Arenas, Bernardo Krause, Dino Giussani

3:45 p.m. - 4:00 p.m.

President's Presenter Award
O-006: Adrenomedullin Levels at Mid-Pregnancy Associate with Fetal Size: Implications for Gestational Diabetes
Cynthia Gonzalez, Lena Shay, Simone Hernandez-Ruano, Matthew Carroll, Madhu Chauhan, Chandra Yallampalli, Kathleen Pennington

4:00 p.m. - 4:15 p.m.

O-007: Impact of Fetal Care Centers on Diagnostic Accuracy of Fetal Anomalies: Comparison at Referral, Multidisciplinary Evaluation, and NICU Discharge
Allan Barraza, Rabbia Imran, Deion Pena, Allyson Montalvo, Henry Galan, Nicholas Behrendt, Sarkis Derderian, Regina Reynolds, Virginia Lijewski, Michael Zaretsky

4:15 p.m. - 4:30 p.m.

O-008: Body Composition In the Second and Third Trimester Of Pregnancy: Comparison Between Women With and Without Gestational Diabetes.
Ilaria Pozzi, Valeria Maggi, Serena Cerri, Gabriele Rossi, Enrico Ferrazzi, Irene Cetin

4:30 p.m. - 4:45 p.m.

O-009: Association Between Food Insecurity and Progression from A1 to A2 Gestational Diabetes Mellitus in a Native Hawaiian/Pacific Islander Population
La-Tisha Frazier, Elizabeth Mercer, Ryenne Ching, Roxanne Erolin, Lauren Kirkwood-Johnsoon, Yixin Chen, Corrie Miller

4:45 p.m. - 5:00 p.m.

O-010: Reducing Neonatal Hypoxic Ischemic Encephalopathy Across a Large University Health System
Donna Neale, Crystal Hicks, Pablo Argeles, Erin Lock, Courtney Townsel, Irina Burd

5:00 p.m. - 5:15 p.m.

O-011: Magnetic Induction Spectroscopy as a tool for detecting cervical remodelling to predict preterm birth findings of a pilot study.
Brenda Narice, Laura Wharton, Jill Tozer, Jamie Healey, Anthony Barker, Brian Brown, Dilly Anumba

5:15 p.m. - 5:30 p.m.

O-012: Impact of Antepartum Bleeding on Neonatal Outcomes in Patients with Placenta Previa  
Joyce Liu, Anthony Melendez-Torres, Adwoa Baffoe-Bonnie, Kathleen Chang, Lillian Boettcher, Anne West Honart, Sarah Dotters-Katz

Gynecology I

Moderators:
Caroline Mitchell, MD, MPH
Yuliya Klymenko, MD, PhD

103

3:30 p.m. - 3:45 p.m.

O-013: Anti-Fibrotic Treatments Attenuate Lesion Establishment, Inflammation, and Hyperalgesia in Mouse Endometriosis
Kanako Hayashi, Mingxin Shi, Madeleine Harvey, Taylor Page, James MacLean

3:45 p.m. - 4:00 p.m.

O-014: CD47 and CDK2 Pathways as Therapeutic Targets in Endometriosis Subtypes: Insights from Transcriptomic Meta-Analysis.
Monika Golinska, Aleksander Rycerz, Piotr Kulesza, Wojciech Fendler

4:00 p.m. - 4:15 p.m.

O-015: Longitudinal Analysis of Circulating Transfer RNA Related Fragment (tRF) Abundance During Experimental Endometriosis Progression in Baboons
Hanna Surmann, Ramanaiah Mamillapalli, Niraj Joshi, Maria Ariadna Ochoa Bernal, Gregory Burns, Asgerally Fazleabas, Hugh Taylor

4:15 p.m. - 4:30 p.m.

O-016: Parsing c-Jun N-Terminal Kinase Inhibitor Responses in Microphysiological Models of Endometriosis
Lauren Pruett, Laura Bahlmann, Sean Pascoe, Ryan Ogi, Angela Jiao, Steve Palmer, Linda Griffith

4:30 p.m. - 4:45 p.m.

O-017: How distinct are endometriosis and adenomyosis from the eutopic endometrium? Insights from spatial transcriptomics
Katie Jones, Christopher Hill, Emily Johnson, Eva Caamano-Gutierrez, Ilyas Arshad, Shakil Ahmed, Dharani Hapangama

4:45 p.m. - 5:00 p.m.

O-018: Spontaneous Ovarian Endometrioma Mouse Model Exhibits Estrogen Responsiveness and Progesterone Resistance.
Yuliya Klymenko, Christine Ramiro, Soumya Gupta, Oyinkasola Adebomojo, Jillian Wendel, Xiyin Wang, Robert Emerson, Shannon Hawkins

5:00 p.m. - 5:15 p.m.

O-019: Investigating the Role of Defensins in Vaginal Epithelial Defense Against Bacterial Vaginosis
Maliha Batool, Nicole De Nisco, Xintong Dong

5:15 p.m. - 5:30 p.m.

O-020: Fibroids Modify the Endometrial Transcriptome: Challenging Uniform Abnormal Uterine Bleeding (AUB) Care
Varsha Jain, Florent Petitprez, Jessica Chung, Pia Wahi-Singh, Aleksandra Tsolova, Peter Rogers, Hilary Critchley

Parturition I

Moderators:
Tamas Zakar, MD, PhD
Mariano Colon-Caraballo, PhD

102

3:30 p.m. - 3:45 p.m.

President's Presenter Award
O-021: IL-9 at the Maternal-Fetal Interface Reveals an Immune Etiology for Preterm Labor of Unknown Cause
Eva Kareus, Roberto Romero, Yi Xu, Roger Pique-Regi, Jose Galaz, Nardhy Gomez-Lopez

3:45 p.m. - 4:00 p.m.

President's Presenter Award
O-022: Translating small format direct on-swab DESI-MS profiling into Clinical Decision-Making for Pregnancy Care
Eftychios Manoli, Gonçalo Correia, Lianne Chapman, Lucia Riaposova, Sherrianne Ng, Tom Bourne, Zoltan Takats, Phillip Bennett, David MacIntyre

4:00 p.m. - 4:15 p.m.

O-023: Environmental Exposures Promote Myometrial Senescence with Implications for Preterm Birth 
Eden Cohen, Magdaleena Mbadhi, Amanda Kallen, Antonina Frolova, Shannon Whirledge

4:15 p.m. - 4:30 p.m.

Early Career Investigator Award
O-024: Maternal Interleukin-22 Gene Delivery Reduces Fetal Inflammation In a Mouse Model Of Ascending Vaginal Infection
Nathalie Kwan, Samantha Brain, Sophia D’Alessandro, Ajda Kašca, Rania Shah, Anna Keegan, Juan Antinao Diaz, Rajvinder Karda, Simon Waddington, Ashley Boyle

4:30 p.m. - 4:45 p.m.

O-025: Maternal body mass index and chorioamnionitis modulate the activin-inhibin-follistatin system in preterm delivery human placentae
Nycolle I. S. Souza, Luana A. B. Silva, Hailey Scott, Bruno G. Anjos, Cherley B V Andrade, Fernando M. Reis, Enrrico Bloise, Kristin L Connor

4:45 p.m. - 5:00 p.m.

The Kusum Lata Excellence Award
O-026: Establishing an Inducible NR4A1 Knockdown Model to Investigate Myometrial Transcriptional Regulators
Saloni Modi, Jennifer Mitchell, Nawrah Khader, Oksana Shynlova, Anna Dorogin

5:00 p.m. - 5:15 p.m.

O-027: Administration of Proteins Secreted by the Placenta Markedly Improves Cerebellum Molecular markers of brain development in Premature Guinea Pigs
Avery Kramer, Kelsey Faer, Rebecca Dyson, Alice Freeman, Theresa Powell, Mary Berry, Thomas Jansson

5:15 p.m. - 5:30 p.m.

O-028: The Impact of Clinical Phenotype of Mid-Trimester Pregnancy Loss on Subsequent Pregnancy Outcomes
Elody Huelmo, Benjamin Brennan, Amrit Dhanushkoti, Andrew Barker, Carl Fayad, Nasser Otutaha, Frances Asence, Lucy Richards, Carol Wang, Craig Pennell

Placenta I

Moderators:
Sylvie Girard, PhD
Esteban Dominguez, DVM, PhD

208

3:30 p.m. - 3:45 p.m.

President's Presenter Award
O-029: Transcriptional Landscape of the Macaque Maternal-Fetal Interface 
Andrea Wegrzynowicz, Jessica Vazquez, Michelle Koenig, Aleksandar Stanic, Jenna Schmidt

3:45 p.m. - 4:00 p.m.

President's Presenter Award
O-030: A dynamic tunable placenta-derived matrix enables long-term culture of a vascularized, immune-competent 3D human mini-placenta model
Sahar Ghorbanpour, Rui Zhou, Dagmar Brislinger, Christian Baumgartner

4:00 p.m. - 4:15 p.m.

O-031: Notch1 Signaling in Placentas from Pregnancies Complicated by Fetal Congenital Heart Defects
Alyssa Tipler, Helen Jones

4:15 p.m. - 4:30 p.m.

O-032: Isthmin2 is essential for extravillous trophoblast (EVT) invasion and low first trimester levels predict PE and FGR
Ruoyu Miao, Sung Gong, Ulla Sovio, Irving Aye, Giulia Avellino, Jacqueline Guettler, Stephanie Rogers, Emma Cook, Paul Kirk, D Stephen Charnock-Jones, Gordon Smith

4:30 p.m. - 4:45 p.m.

O-033: Progesterone Receptor Regulates Post-Implantation Decidual-Trophoblast Interactions and Placental Development
Shuyun Li, Xuting Wang, Myeongjin Yi, Teresa Mahler, Madhumita Ray, Xin Xu, Julie Foley, Don Delker, Xiaofei Sun, Francesco DeMayo

4:45 p.m. - 5:00 p.m.

O-034: Development and Validation of Trimester-Specific Placenta-Maternal Interface Organ-on-Chip Models
Pilar Flores-Espinosa, Ana Guimaraes, Ananth Kammala, Soumen Paul, Ramkumar Menon, Lauren Richardson

5:00 p.m. - 5:15 p.m.

O-035: Understanding the Role of Sortilin Related Receptor 1 in Trophoblast Cellular Function and Pathogenesis of Placenta Accreta
Viktoriia Kolesnyk, Jasmine Jathan, Olga Grechukhina, Miranda Mansolf, Samantha Novo, Derin Bahtiyar, Qing Zuo, Foram Gandhi, Colleen Sinnott, Yang Yang-Hartwich

5:15 p.m. - 5:30 p.m.

O-036: PEG3 Governs Trophoblast Cell Lineage Fate and Placental Growth
Ayelen Moreno Irusta, Esteban Dominguez, Caleb Koontz, Michael Soares

Maternal Biology and Health I

Moderators:
Kathryn Gray, MD, PhD
Jessica Faulkner, PhD

209

3:30 p.m. - 3:45 p.m.

O-037: Weathering & Increasing or Inequitable U.S. Pregnancy-related Mortality Ratios among NonHispanic Black and White women, 2000-2019
Arline Geronimus, John Bound, Landon Hughes, Kanika Harris

3:45 p.m. - 4:00 p.m.

O-038: Anatomical Measurements of the Nonhuman Primate Uterus and Cervix across Gestation: an In Vivo and Ex Vivo Comparative Analysis
Echo Xu, Daniella Fodera, Camilo Duarte-Cordon, Erin Louwagie, Shuyang Fang, Michelle Wyss, Xiaowei Chen, Linsey Carlson, Joy Vink, Ivan Rosado-Mendez, Timothy Hall, Kristin Myers

4:00 p.m. - 4:15 p.m.

O-039: First Trimester Maternal Body Mass Index as Predictor of Hypertensive Disorders of Pregnancy and Gestational Diabetes: The Rotterdam Periconception Cohort.
Lotte Boone, Melek Rousian, Régine Steegers-Theunissen, Sten Willemsen, Ageeth Rosman, Rianne de Bruin

4:15 p.m. - 4:30 p.m.

President's Presenter Award
O-040: Long QT Syndrome Mutations Reduce Potassium Channel-dependent Vasodilation in Human Uteroplacental Resistance Vessels
Ramón Lorca, Germán Arenas, Manesha Putra, Christine Formento, Colleen Julian, Bettina Cuneo

4:30 p.m. - 4:45 p.m.

O-041: Role of Hypothalamic Oxytocin Receptor in Mediating Long-term Maternal Cardiovascular Benefits after Lactation
Ishani Eniyan, Genna Mountcastle, Ariana Samaniego, Madi Lay, Meera Rath, Egle Bytautiene Prewit

4:45 p.m. - 5:00 p.m.

O-042: Recovered Acute Kidney Injury Further Impairs Renal and Placental Efficiency in ACE2 Knockout Mice
Jessica Hebert, Adam Munhall, Paris Harrell, Susan Gurley, Michael Hutchen

5:00 p.m. - 5:15 p.m.

O-043: Pelvic Floor Muscle Regeneration Following Simulated Birth Injury Is Impacted By Pregnancy And Lactation In Preclinical Rat Model
Bianca Pena, Karen Christman, Marianna Alperin

5:15 p.m. - 5:30 p.m.

O-044: Preventability analysis of maternal deaths due to obstetric critical hemorrhage in Japan: A review of 22 recent cases reported to the nationwide registration system
Shinji Katsuragi, Hiroaki Tanaka, Junichi Junichi, Kayo Tanaka, Tatsuya Arakaki, Masamitsu Nakamura, Tomoaki Oda, Masafumi Nii, Masahiko Nakata, Takeshi Murakoshi, Akihiko Sekizawa, Isamu Ishiwata, Tomoaki Ikeda

Reproductive Biology I

Moderators:
Paulo Rinaudo, MD, PhD
Patricia Diaz Gimeno, PhD

104

3:30 p.m. - 3:45 p.m.

President's Presenter Award
O-045: The impact of ultra-low oxygen IVF on preimplantation and postnatal development Cassidy Hemphill, Eric Rhon-Calderon, Alexandra Savage, Ana Domingo Muelas, Nicolas Platcha, Marisa Bartolomei

3:45 p.m. - 4:00 p.m.

President's Presenter Award
O-046: PGRMC2 deficiency impairs placental development and contributes to stillbirth through mitochondrial dysfunction and PKC?-mediated defects in trophoblast fusion
Fumei Gao, Shuang Liang, Liping Feng

4:00 p.m. - 4:15 p.m.

O-047: Müllerian duct maintenance at the cranial region is dependent upon GATA2
Fei Zhao, Shuai Jia

4:15 p.m. - 4:30 p.m.

O-048: Enhanced Epididymal Epithelial Cell Secretory Activity Improves Germ Cell Function and Fertility.
Kerstin Creutzberg, Alyssa Jeng, Tracy Bale

4:30 p.m. - 4:45 p.m.

President's Presenter Award
O-049: A DNA Repair-Dependent Mechanism of Male Infertility 
Yaxi Wang, Ya-Chin Yang

4:45 p.m. - 5:00 p.m.

O-050: Engineering Thick, Vascularized Uterine Tissues On Chip.
Kayla Wolf, Pei Wen Xiao, Anais Del Rosario, Pooja Nair

5:00 p.m. - 5:15 p.m.

O-051: A Novel Optogenetic Model for Smooth Muscle-Driven Vasodilation in the Pregnant Mouse Uterine Vasculature
Germán Arenas, Christine Formento, Lorna Moore, Colleen Julian, Diego Restrepo, Ramón Lorca

5:15 p.m. - 5:30 p.m.

O-052: Metabolic Regulation of Spermatogonial Stem Cells and Progenitor Spermatogonia
Katerina Damyanova, Brett Nixon, Joshua Fisher, Siddharth Acharya, Tessa Lord

5:45 p.m. - 7:15 p.m.

Ballroom B

Connection Corners is a ticketed event and will be available for pre-registration via the online registration process.
Pre-registration for Connection Corners is ONLY available for In Training Members. A limited number of tickets will be available onsite at the registration desk.
During this event, accomplished senior members are invited to host discussions at tables with topics that are relatable and of interest to attendees at diverse stages in their careers. These open-ended “chats” provide a casual environment to interact, and facilitate networking between meeting attendees, especially amongst trainees.

5:45 p.m. - 7:15 p.m.

208

Moderator:
Erica E. Marsh, University of Michigan

Panelists:

Melissa Simon, MD, MPH
Professor, Vice Chair Research, Director ELEVATE Lab
Northwestern University SOM

David R. Williams, MPH, PhD
Florence & Laura Norman Professor of Public Health
Department of Social & Behavioral Sciences, Harvard T.H. Chan School of Public Health
Professor of African and African American Studies and of Sociology
Harvard University

Kathleen A. Connell, MD
Professor, Division Chief
William B. Goddard, MD Endowed Professor in Urogynecology
Divisions of Urogynecology & Reconstructive Pelvic Surgery and Reproductive Sciences
Department of Obstetrics and Gynecology
University of Colorado

7:00 a.m. - 6:00 p.m.

Registration

Level II Mezzanine

8:00 a.m. - 8:10 a.m.

Ballroom A

8:10 a.m. - 9:00 a.m.

Ballroom A

9:00 a.m. - 11:00 a.m.

Hall A

11:00 a.m. - 12:30 p.m.

104

11:00 a.m. - 11:15 a.m.

Early Career Investigator Award
O-053: Sperm DNA methylation alterations from delta-9-tetrahydrocannabinol use are evident in offspring
Rahul D'Mello, Lyndsey Shorey-Kendrick, R. Clayton Edenfield, Olivia Hagen, Michael Davies, Charles Easlery, Jason Hedges, Carol Hanna, Jamie Lo

11:15 a.m. - 11:30 a.m.

O-054: Preeclampsia Leptin Model Shows Loss of Circadian Rhythm and Angiotensin-Induced Blood Pressure Variability Only in Male Offspring
Mona Elgazzaz, Sydney Prusak, Gabrielle Hernandez, Puja Punukollu, Gibson Cooper, Amalia Brawley, Desmond Moronge, Jessica Faulkner

11:30 a.m. - 11:45 a.m.

Laxmi Baxi Award
O-055: Divergent Effects of Melatonin on Oxycodone-Induced Fetal Growth Restriction and Apoptosis in the Fetal Brain.
Isaac Adediji, Hager Kowash, Pegah Nouri Mousa, Christianah Aloba, Victoria Schaal, Gurudutt Pendyala, Lynda Harris

11:45 a.m. - 12:00 p.m.

O-056: Maternal Allergen Exposure Leads to Sex-Dependent Immune Cell Dysfunction During Airway Inflammation.
Kaitlin McKernan, Jacqueline Cephus, Shelby Kuehnle, Emely Henriquez Pilier, Andrew Peebles, Allison Norlander, Stokes Peebles, Jr., Dawn Newcomb

12:00 p.m. - 12:15 p.m.

O-057: Mitochondria-Targeted Protection Against Cardiac Dysfunction in an Embryonic Model of Intermittent Hypoxia During Development
Marzieh Eshagh-Nimvari, Youguo Niu, Sage Ford, Sara Perelmuter, Natasha Cavell, Jack Barry, Anna Cochrane, Mike Murphy, Dino Giussani

12:15 p.m. - 12:30 p.m.

O-058: Adverse Pregnancy Outcomes Induced by Maternal Regulatory T Cell Deficiency in the Peri-implantation Period Program Altered Cardiometabolic Function in Male Offspring.
Stacey Savin, Evangeline Lovell, Amy Wooldridge, Shanna Hosking, Rianna De Poi, Lisa Nicholas, Matthew Chapman, Sven Surikow, Laura Parry, Lachlan Moldenhauer, Sarah Robertson, Alison Care

Fetus I

Moderators:
Sandra Davidge, PhD, FCAHS, FRSC
Kimberley Botting-Lawford, PhD

101

11:00 a.m. - 11:15 a.m.

O-059: Persistence of cell-free DNA From the Demised Fetus In Vanishing Twin Pregnancies
Lorraine Dugoff, Nicholas Sun, Ebad Ahmed, Thea Golden, Kathleen Kueck, Anastasia Butskova, Sunni Mumford, Wenbo Xu, Jeffrey Meltzer, Vivienne Souter

11:15 a.m. - 11:30 a.m.

O-060: Tadalafil Therapy for Fetal Vascular Dysfunction: Studies in the Chicken Embryo
Shintaro Maki, Youguo Niu, Anna Cochrane, Skaai Davison, Clement Cahen, Sage Ford, Eiji Kondo, Tomoaki Ikeda, Dino Giussani

11:30 a.m. - 11:45 a.m.

President's Presenter Award
O-061: Acute Maternal Placental Lactogen Infusion Promotes Fetal Amino Acid Delivery by Reducing Placental Amino Acid Utilization.
Amelia Tanner, Marjorie Nguyen, Russell Anthony, Paul Rozance

11:45 a.m. - 12:00 p.m.

O-062: Transdermal and Intramuscular Administration of Antenatal Steroids Elicit Distinct Cardiac Functional and Transcriptomic Responses in a Sheep Model of Pregnancy
Yusaku Kumagai, Sean Carter, Erin Johnson, Hannah Watson, Noriyoshi Mochii, Haruo Usuda, Masatoshi Saito, Matthew Kemp

12:00 p.m. - 12:15 p.m.

President's Presenter Award
O-063: Estrogen Affects Neuron-Microglia Crosstalk Through Inflammasome Regulation in the Non-Human Primate Fetal Brain
Sahar Khoshravesh, Anguo Liu, Kristina Witcher, Arya Rahimi, Jeffery Babischkin, Eugene Albrecht, Courtney Townsel, Graham Aberdeen, Jun Lei, Irina Burd

12:15 p.m. - 12:30 p.m.

O-064: Objective Fetal Movements are related to maternal characteristics
Sohini Patel

Preeclampsia I

Moderators:
Simcha Yagel, MD
Jessica Hebert, PhD

209

11:00 a.m. - 11:15 a.m.

O-065: Endothelin-1 in Preeclampsia: Pathogenesis and Therapeutic Potential
Natalie Hannan, Natalie Binder, Natasha de Alwis, Zoe Kodila, Bianca Fato, Christine Farah, Sally Beard, Teresa MacDonald, Sue Walker, Stephen Tong, Tu'uhevaha Kaitu’u-Lino

11:15 a.m. - 11:30 a.m.

O-066: Preeclamptic iPSC-Derived Endothelial Cells Exhibit Global Dysfunction With Heterogeneous Defects In Nitric Oxide Signaling and Vascular Barrier Integrity
Xi Plummer, Yanming Wu, Purnima Iyer, Nazish Sayed, Virginia Winn

11:30 a.m. - 11:45 a.m.

O-067: PAI1 Promotes Maternal Endothelial Dysfunction in a Mouse Model of Preeclampsia.
Gjina Ahmetaj, Rachel Hauschel, Seth Guller, Anne Eichmann, Molly McAdow

11:45 a.m. - 12:00 p.m.

O-068: MitoQ Blunts Human Uteroplacental Vasoconstriction With Enhanced Effects in Preeclampsia and at High Altitude
Ramón Lorca, Katie O'Brien, German Arenas, Camila Elias, Julie Houck, Fernando Abastoflor, Carmen Abastoflor, Valquiria Miranda-Garrido, Lorna Moore, Alex Nina, José Aguilar Jiménez, Lilian Toledo-Jaldin, Colleen Julian

12:00 p.m. - 12:15 p.m.

O-069: Mapping Maternal-Fetal Cellular Cross-Talk in Preeclampsia at Single-Cell Resolution Seungbaek Lee, Roberto Romero, Jose Galaz, Adi Tarca, Gaurav Bhatti, Eloise Eyestone, Roger Pigue-Regi, Nardhy Gomez-Lopez

12:15 p.m. - 12:30 p.m.

O-070: HnRNPC1/C2 as a key epigenetic modulator of vitamin D signaling in endothelial cells associated with preeclampsia
Jie Xu, David Lewis, Dani Zoorob, Danielle Cooper, Yuping Wang

Gynecology II

Moderators:
Zaher Merhi, MD, HCLD
Jaime Roura-Monllor, MD, PhD

103

11:00 a.m. - 11:15 a.m.

O-071: Predictive Value of Uterine Peristalsis Patterns for Pregnancy Outcomes at the Time of Frozen Embryo Transfer.
Josephine Lau, Courtney Murphy, Rand El Sharaiha, Zezhen Xiang, Qiuchang Sun, Qing Wang, Yong Wang, Valerie Ratts

11:15 a.m. - 11:30 a.m.

President's Presenter Award
O-072: The Utility of Dual Point-of-Care Syphilis and HIV Screening in First-Line Women's Clinics in a Medically Under - Resourced Community
Christina Cortes, Rachel Hauschel, Sahana Kodali, Jimena Balderas-Berg, Twyla Brack, Robin Beach, Philip Johnson, Irene Stafford

11:30 a.m. - 11:45 a.m.

O-073: Association Between Age of Symptom Onset and Delayed Diagnosis of Endometriosis in Puerto Rico: A Cross-Sectional Study
Tatiana Perez-Rodriguez, Cruz Nazario, Gilberto Ramos-Valencia, Ana Lugo-Rubio, Idhaliz Flores-Caldera

11:45 a.m. - 12:00 p.m.

O-074: Exploring Zinc as an Alternative to Copper in Non-Hormonal Intrauterine Devices: Evaluating Contraceptive Efficacy in Human Sperm
Ava Ospina, Aaron Lazorwitz, Manasa Basavaraju

12:00 p.m. - 12:15 p.m.

O-075: Estrogen-Mediated Host-Pathogen Response to Uropathogenic Escherichia coli in Bladder Epithelial Cells
Fernando Beserra, Lina Loza, David Danforth, Humberto Escobedo, Annika Smith, Ariel Chen, Joshua Johnson, Kathleen Connel, Michael Schurr, Marsha Guess

12:15 p.m. - 12:30 p.m.

O-076: Pre-Fibroid Screening: Urinary G-CSF as a Non-Invasive Marker of Fibroid-Prone Myometrium.
Saba Haq, Leen Alsoud, Mervat Omran, Mohamed Ali, Fatimah Abdulnaser Hussein, Everett Tate, Obianuju Sandra Madueke Laveaux, Mira Mousa, Ayman Al-Hendy

Parturition II

Moderators:
Egle Prewit, MD, PhD

102

11:00 a.m. - 11:15 a.m.

Early Career Investigator Award
O-077: SPDEF is required for cervical goblet cell differentiation and mucus production
Yevgenia Fomina, Elizabeth Payne, ShanmugaPriyaa Madhukaran, Mala Mahendroo

11:15 a.m. - 11:30 a.m.

President's Presenter Award
O-078: BSCI resolves inflammation in human myometrium via induction of CREB and Annexin signalling
Adam Boros-Rausch, Oksana Shynlova, Stephen Lye

11:30 a.m. - 11:45 a.m.

Laxmi Baxi Award
O-079: Synthetic Mucins Attenuate Pathogen-Induced Inflammatory Signaling in Reproductive Epithelium
Amanda Ojeda, Arianna Tamura, Marissa Veeravagu, Jessica Xhumari, Luiz Wurdig Roesch

11:45 a.m. - 12:00 p.m.

O-080: High Glucose Exposure Induces Differential Pathophysiologic Changes In Feto-Maternal Interface Cells
Glenmarie Angelica Perias, Ana Paula Pereira Guimaraes, Ourlad Alzeus Tantengco, Leslie Michelle Dalmacio, Lauren Richardson, Ananth Kumar Kammala, Ramkumar Menon

12:00 p.m. - 12:15 p.m.

O-081: Methadone Triggers Fetal Membrane Sterile Inflammation Through Innate Immune Signaling
Megan Kelleher, Hanah Georges, Lily Salmeron, Ryan Logan, Kimberly Yonkers, Vikki Abrahams

12:15 p.m. - 12:30 p.m.

O-082: Uterine-targeted PLGA nanoparticle-based formulation of tocolytic agents
Camille Trinidad, Andrew Cothrell, Christopher Hansen, Lauren Link, Alexus Brown, Jennifer Herington, Todd Giorgio

Reproductive Endocrinology and Infertility I

Moderators:
Sarah Berga, MD
Limor Man, MD, M.Med.Sc

208

11:00 a.m. - 11:15 a.m.

O-083: Use of hormonal contraceptives and metformin therapy for 24 weeks impacts 11oxy-androgens in women with polycystic ovary syndrome
Anuja Dokras, Christina Stetter, Allen Kunselman, Richard Legro

11:15 a.m. - 11:30 a.m.

President's Presenter Award
O-084: Development of a novel immunodeficient prenatal mouse model of polycystic ovary syndrome for evaluation of new therapeutics
Camille Gauthier, Haojiang Lu, Sara Torstensson, Eva Lindgren, Claes Ohlsson, Anna Benrick, Elisabet Stener-Victorin

11:30 a.m. - 11:45 a.m.

O-085: E-Cigarette Vapor Impairs Erectile Tissue and Reduces Seminiferous Tubule Size
Samuel Cripps, Elizabeth Fein, Margeaux Marbrey

11:45 a.m. - 12:00 p.m.

O-086: The diametric effects of chemotherapy induced Sertoli cell-derived EVs in the prepubertal testis: driving apoptosis in Sertoli cells and chemoprotection to germ cells
Michael Rimmer, Christopher Gregory, Rod Mitchell

12:00 p.m. - 12:15 p.m.

O-087: Transcriptomic Consistency in Endometrial Biopsies: Evidence Across Cycles and Tissue Portions
Asunta Martinez-Martinez, Patricia Sebastian-Leon, Laura Caracena, Pilar Alama, Patricia Diaz-Gimeno

12:15 p.m. - 12:30 p.m.

O-088: Basal Inflammation is Adiposity-Related While Nutrient-Induced Inflammation is Independent of Adiposity in Polycystic Ovary Syndrome (PCOS).
Robert V. Considine, Ana-Leonor Jay, Anthony Acton, Jiaping Xue, Lixin Qi, Frank Gonzalez

12:30 p.m. - 1:30 p.m.

208

Panelists:

Hilary Critchley, MD, DSc, FRCOG
Professor of Reproductive Medicine
Consultant Gynaecologist, NHS Lothian
The University of Edinburgh

E. Albert Reece, MD, PhD, MBA
CARTI Endowed Professor, Obstetrics, Gynecology and Reproductive Sciences
Director, Center for Advanced Research Training and Innovation (CARTI)
Senior Scientist, Center for Birth Defects Research
University of Maryland School of Medicine

Idhaliz Flores, PhD
Professor
Ponce Health Sciences University - Ponce Research Institute

12:30 p.m. - 1:30 p.m.

209

Shifa Turan MD, RDMS
Professor
Director, Fetal Heart Program
Department of Obstetrics, Gynecology and Reproductive Sciences
University of Maryland School of Medicine

Aleksandar Stanic-Kostic MD, PhD
Associate Professor, Vice Chair for Basic and Translational Research, Department of Ob/Gyn
Division Director of Reproductive Sciences
Division of Reproductive Endocrinology and Infertility
University of Wisconsin-Madison

Jeffrey S. A. Stringer, MD, FACOG
Division Director, Global Women's Health
Professor, Global Women's Health
Adjunct Professor, Epidemiology
University of North Carolina - Chapel Hill

1:45 p.m. - 3:45 p.m.

G protein-coupled receptors (GPCRs):  A New Frontier in Reproductive Repair and Renewal 

Moderators:
Antonina I. Frolova, MD, PhD
Moderator II

101

1:45 p.m. - 2:15 p.m.

Cell biology and pharmacology of G protein-coupled receptors (GPCRs)
JoAnn Trejo, PhD
University of California, San Diego

2:15 p.m. - 2:45 p.m.

Regulation of G protein-coupled receptors in Cyclic Endometrial Renewal
Steven L. Young, MD, PhD
Duke University

2:45 p.m. - 3:15 p.m.

The Role of G protein-coupled receptors in Ovarian Metabolic Function
John Davis, PhD
University of Nebraska Medical Center

3:15 p.m. - 3:45 p.m.

Myometrial beta 3-adrenergic receptors as part of a novel tocolytic strategy
Scott Barnett, PhD
University of Nevada, Reno

Silent Guardians: Macrophages of the Reproductive Tract

Moderators:
Christina Megli, MD, PhD
Moderator II

102

1:45 p.m. - 2:15 p.m.

Macrophages of the Reproductive Tract- the good and the bad
David Aronoff, MD
Indiana University School of Medicine

2:15 p.m. - 2:45 p.m.

The role of Macrophages in Vaginal Response to Graft Materials 
Amanda Artsen, MD
University of Pittsburgh

2:45 p.m. - 3:15 p.m.

Macrophage Polarization in Endometriosis
Osamu Yoshino, MD
University of Yamanashi, Obstetrics and Gynecology

3:15 p.m. - 3:45 p.m.

Role of placental macrophages in inflammation and preterm birth
Sylvie Girard, PhD
Mayo Clinic

Tissue Engineering for Functional Repair of Reproductive Tract

Sponsored by Magee-Womens Research Institute and Foundation

Moderators:
Irene Cervello, PhD
Hannah Zierden, PhD

103

1:45 p.m. - 2:15 p.m.

Tissue Engineering of Functional Reproductive Organs
Anthony Atala, MD
Wake Forest University

2:15 p.m. - 2:45 p.m.

Leveraging micro-mold technology for vaginal regeneration
Pamela Moalli, MD, PhD
Magee-Womens Research Institute

2:45 p.m. - 3:15 p.m.

Importance of Patient-Specific Material Properties for Regeneration of Reproductive Tissues
Kristin Myers, PhD
Columbia University

3:15 p.m. - 3:45 p.m.

Tissue engineering the endometrial 3D microenvironment
Linda Griffith, PhD
Massachusetts Institute of Technology

Extracellular Vesicles in Reproductive Health

Sponsored by Perinatal Research Society

Moderators:
Moderator I
Moderator II

104

1:45 p.m. - 2:15 p.m.

Maternal Circulatory EVs: a window to the fetus 
Laura Goetzl, MD
University of Texas, Health Sciences Center at Houston

2:15 p.m. - 2:45 p.m.

Menstrual Fluid-Derived Extracellular Vesicles in Gynecologic health and Disease
Caroline Gargett, PhD
Hudson Institute of Medical Research

2:45 p.m. - 3:15 p.m.

Extracellular vesicles in liquid biopsy: innovative analytic approaches
Hakho Lee, PhD
Massachusetts General Hospital - Center for Systems Biology
Harvard Medical School

3:15 p.m. - 3:45 p.m.

Miniaturized Workflows for Transcriptomic Profiling of Extracellular Vesicles for Biomarker Discovery in Pregnancy Disorders
Priya Pantham, PhD
University of California, San Diego

3:45 p.m. - 4:00 p.m.

Level I Foyer

4:00 p.m. - 5:30 p.m.

The Future of Reproductive Regenerative Medicine

Moderators:
Leslie Myatt, PhD, FRCOG

209

4:00 p.m. - 4:15 p.m.

O-089: Novel Strategy to Generate Healthy Human Ovarian Organoids from Cryopreserved Ovarian Cortex Tissue.
Clara Bueno-Fernandez, Nadaya Corpas, María Gómez-Álvarez, Marcos Agustina-Hernández, Paula Alonso-Frías, Emilio Francés-Herrero, Amparo Faus, Antonio Pellicer, Irene Cervelló

4:15 p.m. - 4:30 p.m.

O-090: Exofection by Trophoblast Extracellular Vesicles Restores Transporter Function: A Novel Therapeutic Paradigm Bridging Reproductive Biology and Neurodegeneration
Ananth Kammala, Madhuri Tatiparthy, Sravan Gopala Krishna Shetty Sreenivasmurthy, Lauren Richardson, Balaji Krishnan, Ramkumar Menon

4:30 p.m. - 4:45 p.m.

O-091: Spatial Transcriptomics of Mouse Testicular Tissue Reveals the Critical Role of Exosomes in Protecting Germ Cells and Promoting Spermatogenesis Through Sertoli-Leydig Synchronization
Farzana Liakath Ali, Mervat Omran, Omer Raheem, Ayman Al-Hendy

4:45 p.m. - 5:00 p.m.

O-092: Modeling Innate Immune Interactions in a Modular Cervix Microphysiologic System.
Katherine Nelson, Filipa Ribeiro, Ian Glomski, Alison Criss, Jason Gleghorn

5:00 p.m. - 5:15 p.m.

O-093: Class Imbalanced Data on Misleading Accuracy and Precision in AI-Driven Preterm Birth Prediction.
Shan Liu, James Yang, Peixin Yang, Fuhua Xu

5:15 p.m. - 5:30 p.m.

Benign & Malignant Tumors

Moderators:
Mostafa Borahay, MD, PhD
Emmanuel Paul, MS, PhD

102

4:00 p.m. - 4:15 p.m.

SRI-Bayer President's Presenter Award
O-095: Engineering a 3D In Vitro Model of Uterine Fibroids to Enable Small Molecule Therapeutic Screening
Allison Moses, Miriam Tamano de Blanco, Erika Moore

4:15 p.m. - 4:30 p.m.

SRI-Bayer President's Presenter Award
O-096: Handbrake on Hysterectomy: Multi-Omics Mapping of Uterine Fibroids to Enable Personalised Fertility-Preserving Therapeutics
Lorna Salvini, Karla Paterson, Christopher Hill, Mairi Sandison, Michele Zagnoni, Joscelyn Harris, Steven Robinson, Andrew Davidson, Emily Johnston, Eva Caamano Gutierrez, Dharani Hapangama

4:30 p.m. - 4:45 p.m.

O-097: Examining the Shared Genetic Architecture of Uterine Fibroids and Keloid Scars.
Catherine Greene, Toni Lewis, Gabrielle Hampton, Jeewoo Kim, Elizabeth Jasper, Jacklyn Hellwege, Todd Edwards, Digna Velez Edwards

4:45 p.m. - 5:00 p.m.

O-098: Integrated Lipidogenomic Evaluation of Arachidonic Acid Metabolism in Uterine Leiomyomas
Santoshi Gondi, Begum Mathyk, Xiaofang Guo, Kosha U padhyaya, Brittney Short, Thomas J. Rutherford, Matthew Anderson

5:00 p.m. - 5:15 p.m.

O-099: A Mesenchymal Progenitor Population with Altered Differentiation Potential Underlies Uterine Leiomyoma Formation.
Aymara Mas, Sandra Boldú, Esther Lara, Silvia Bello, Gema Gassó, Carles Moreno, Yasmina Cuartero, Carlos Simón

5:15 p.m. - 5:30 p.m.

O-100: Impact of Anatomical Site on RNA-based molecular subtypes in High-Grade Serous tubo-Ovarian Carcinoma Samples
Karolin Heinze, Tia Murdoch, Evan Cairns, Aline Talhouk, Ulrich Canzler, Jalid Sehouli, Sven Mahner, Philipp Harter, Jacobus Pfisterer, Stefan Kommoss, Michael Anglesio

Reproductive Biology II

Moderators:
Monica Mainigi, MD
Yong Song, MD, PhD

104

4:00 p.m. - 4:15 p.m.

O-101: Altered Endometrial-Placental Communication in Uteri with Prior Cesarean Scar
Halina Yee, Anhyo Jeong, Guadalupe Martinez, Rebecca Zhu, Shibo Zhou, Yuka Fukuda, Sohum Shah, Feiyang Ma, Yalda Afshar

4:15 p.m. - 4:30 p.m.

O-102: Uterine Natural Killer Cells Mediate Endometrial Stromal Cell Inflammation and Remodeling During Decidualization in a Menstrual-Effluent Derived Model.
Stephanie Busch, Andrew Shih, Rixsi Herrera, Laurianna Frasson, Houman Khalili, Polona Safaric-Tepes, Peter Gregersen, Christine Metz

4:30 p.m. - 4:45 p.m.

O-103: Modeling Early Human Placentation and Embryo-Endometrial Crosstalk In Vitro
Matteo Molè, Sarah Elderkin, Irene Zorzan, Christopher Penfold, Nicole Horsley, Francisco Domínguez, Peter Rugg-Gunn

4:45 p.m. - 5:00 p.m.

O-104: Type V collagen is necessary for endometrial decidualization and angiogenesis during embryo implantation
Mona Gebril, Emily Kinneston, Rimi Das, John Lydon, Shanmugasundaram Nallasamy

5:00 p.m. - 5:15 p.m.

O-105: Circulating miRNAs in adenomyosis mirror eutopic endometrial profiles: potential non-invasive biomarkers
Ana Corachán, Alba Bas-Rivas, Aitana Merino-Pérez, Amparo Faus, Carmen Vidal, Juan Giles, Juan Antonio García-Velasco, Hortensia Ferrero

5:15 p.m. - 5:30 p.m.

O-106: PAR-2 Identified as a Maternal Sensor Orchestrating Embryo Selection and Implantation.
Martina Ciprietti, Joris Vriens

Placenta II

Moderators:
Lynda Harris, PhD, FRCOG
Emmanuel Amabebe, PhD

208

4:00 p.m. - 4:15 p.m.

O-107: The Creatine Kinase System Regulates Energy Metabolism and Growth of Human Trophoblast Cells
Nirvay Sah, Eshanya Gupta, Claire Zheng, Walee Shaik, Donald Pizzo, Francesca Soncin

4:15 p.m. - 4:30 p.m.

O-108: Deficiency of Atrial Natriuretic Peptide is Associated with Adverse Cardiovascular Outcomes in Black Patients and Hypertensive Rats
Anxhela Treska, Gibson Cooper, Safia Ogbi, Elisabeth Mellott, Cayman Bickerstaff, Stephanie Stokes, Amalia Brawley, Desmond Moronge, Mona Elgazzaz, James Maher, Padshmashree Woodham, Jessica Faulkner

4:30 p.m. - 4:45 p.m.

O-109: Placenta-Specific RNA Interference of DIO2 Reveals Significant Placental and Maternal Differences at Midgestation in Sheep.
Sarah Singleton, Kendall Mesch, Adam Chicco, Russell Anthony, Quinton Winger

4:45 p.m. - 5:00 p.m.

O-110: Metabolic Differences Between Lean and Obese Placentas are Maintained in Trophoblast Organoid Cultures
Andrea Woods, Sylvia Wright, Maria Florian-Rodriquez, Weizhi Xu, Nancy De La Cruz, Ashley Solmonson

5:00 p.m. - 5:15 p.m.

O-111: First Trimester Trophoblast Stem Cells Show Differential Transcriptional Regulation with ECM Exposures
Uma Gaffney, Yalda Afshar, Christina Megli

5:15 p.m. - 5:30 p.m.

O-112: Long-Read Isoform Sequencing of Transcripts and Splicing Variants in Placentae of IVF and In Vivo Conceived Mice
Reza Oqani, Emin Maltepe, Paolo Rinaudo

Reproductive Endocrinology and Infertility II

Moderators:
William Catherino, MD, PhD
Jessica Garcia de Paredes, MD

103

4:00 p.m. - 4:15 p.m.

President's Presenter Award
O-113: Risk Factors For Ectopic Pregnancy Following Embryo Transfer: An Analysis Of Sart-Cors Registry (2014-2020)
Jiahui Zhang, Joan Skelly, Jennifer Dundee, Natalie Tikhomirova, Navid Esfandiari, Ellyse Diamond, Jeffrey Peipert, Amanda Kallen

4:15 p.m. - 4:30 p.m.

O-114: Uncovering Incidental Parental Chromosomal Abnormalities Through Preimplantation Genetic Testing for Aneuploidy.
Roni Zemet, Ashley Spector, Hailie Ciomperlik, Laurie McKenzie, Laura Detti, Ignatia Van den Veyver, Sandra Darilek

4:30 p.m. - 4:45 p.m.

O-115: Elevated Endometrial Microplastic Polymers are Associated with Path-Confirmed Path-Endometrial Polyps: Insight on Environmental Exposures and Reproductive Pathology
Irene Peregrin-Alvarez, Hailie Ciomperlik, Megan Alexander, Momal Sharif, Leah Schenk, Ninad Patil, Marcus Garcia, Laurissa Barela, Matthew Campen, Enrico Barrozo, Laura Detti

4:45 p.m. - 5:00 p.m.

President's Presenter Award
O-116: Natural Versus Programmed Endometrium in Fertility Treatment: Transcriptomic Landscape, Angiogenic Balance, and Hypertension in Pregnancy.
David Huang, Emily Flynn, Brittany Davidson, Juan Irwin, Ana Laura Almonte, Jennifer Qin, Yue Song, Fleurdeliza Rabara, Rebecca Wong, Lydia Zablotska, Mitchell Rosen, Gabriela Fragiadakis, Alexis Combes, Marina Sirota, Marcelle Cedars, Linda Giudice

5:00 p.m. - 5:15 p.m.

O-117: The validity of serum anti-Müllerian hormone (AMH) levels as a predictor of ovarian response to controlled ovarian stimulation (OS) decreases after 3 months
Akanksha Garg, Erkan Kalafat, Andres Reig, Baris Ata, Juan Garcia-Velasco, Emre Seli

5:15 p.m. - 5:30 p.m.

O-118: Preterm Birth After Assisted Reproductive Technology in Twins: Are Neonates at Higher Risk of Respiratory Morbidity?
Shareen Patel, Yossi Bart, Hector Mendez-Figueroa

Clinical and Translational Perinatology II

Moderators:
Alireza A Shamshirsaz, M.D., FACOG
Ai-ris Collier, MD

101

4:00 p.m. - 4:15 p.m.

Early Career Investigator Award
O-119: Comparative Effectiveness of Innovative Strategies Versus Traditional Models for Postpartum Blood Pressure Monitoring
Ukachi Emeruwa, Carolina Thorlund-Dίaz, Jingjing Zou, Anushka Edlabadkar, Brittney Charlot, Toluwalasé Ajayi, Bonnie Kaiser, Natalie Bello, Gregory Aarons, Cynthia Gyamfi-Bannerman

4:15 p.m. - 4:30 p.m.

President's Presenter Awards 
O-120: Elective Induction More Common in Maternity Care Deserts: A National Analysis of Access and Utilization
Oladunni Ogundipe, Frank Jackson, Sarah Abelman, Luis Bracero, Matthew Blitz

4:30 p.m. - 4:45 p.m.

O-121: Multidisciplinary Transition Clinic after Hypertensive Disorder of Pregnancy in the Extended Postpartum Period
Isha Vasudeva, Sarah Chiavacci, Ira Bernstein

4:45 p.m. - 5:00 p.m.

O-122: Care in a Preterm Birth Prevention Clinic Reduces the Impact of Mid-Trimester Loss on Subsequent Pregnancy Outcomes
Elody Huelmo, Amrit Dhanushkoti, Benjamin Brennan, Andrew Barker, Carl Fayad, Nasser Otutaha, Carol Wang, Craig Pennell

5:00 p.m. - 5:15 p.m.

O-123: Adverse Maternal and Neonatal Outcomes Among Native Americans in Rural California
Jennifer Murray, Bharti Garg, Michelle Debbink, Aaron Caughey

5:15 p.m. - 5:30 p.m.

O-124: The Impact of Labor Dystocia Related Primary Cesarean Indications on Subsequent Vaginal Birth After Cesarean Delivery in an Underserved Population
Karla Martin, Tala Ghorayeb, Mohamad Maktabi, Mason Collie, Bingrui Chen, GiGi Baer, Hope Murphy-McDaniel, Baha Sibai, Irene Stafford

5:45 p.m. - 7:00 p.m.

Ballroom A

Presidential Address
Irina Burd, MD PhD

Awards Ceremony

• DeCherney Society Lifetime Distinguished Service Award
• President's Achievement Award
• SRI Mentorship Award
• SRI Distinguished Scientist Award

8:30 p.m. - 11:00 p.m.

Ballroom A

7:00 a.m. - 12:00 p.m.

Registration

Level II Mezzanine

7:30 a.m. - 8:15 a.m.

Ballroom A

8:30 a.m. - 10:30 a.m.

Hall A

10:30 a.m. - 12:00 p.m.

Fetus II

Moderators:
Anna David, PhD FRCOG FMedSci
Eileen Chang, PhD

101

10:30 a.m. - 10:45 a.m.

O-125: Maternal Immune Activation Impacts the Pool of Developing Fetal Gamma-Delta T cells
Oliver Dienz, Elizabeth Bonney, Marlana Winschel, Brianna Hilton, Jonathan Boyson

10:45 a.m. - 11:00 a.m.

O-126: Hypoxia-Mimetic DMOG Recapitulates Hypoxia-Induced Embryonic Origins of Growth Restriction and Cardiac Dysfunction
Youguo Niu, Shintaro Maki, Emma Hodson, Clem Cahen, Dino Giussani

11:00 a.m. - 11:15 a.m.

O-127: Role of Pericytes in Modulating Barrier Function of Human Fetal Brain Endothelial Cells, In Vitro
Phetcharawan Lye, Enrrico Bloise, Nikola Ivanovski, Stephen Matthews

11:15 a.m. - 11:30 a.m.

O-128: Identification of stiffness zones under physiological and pathological stretch in human umbilical arteries and their transcriptional influence in endothelial cells under culture conditions
Bernardo Krause, Patricio Morales-Rosales, Matias Carrasco, Claudio Garcia-Herrera, Duvan Henao

11:30 a.m. - 11:45 a.m.

O-129: Maintaining amino acid concentrations during experimental hyperglucagonemia does not improve growth in fetal sheep
Alicia White, Marjorie Nguyen, Amelia Tanner, Paul Rozance

11:45 a.m. - 12:00 p.m.

O-130: Antenatal Influenza and Tdap Vaccination and Child Neurodevelopment at Age 18 to 30 Months
Lynn Yee, Monica Longo

Gynecology III

Moderators:
Buchitra Singh, MD, MPH, MS, MBA

103

10:30 a.m. - 10:45 a.m.

O-131: Smooth Muscle Loss and ECM Remodeling in POP: Links to Menopause and Systemic Inflammation
Lizbeth Grado, Joshua Johnson, David Orlicky, Lauren Rascoff, Saphie Potts, Jamie Arruda, Juana Hutchinson-Colas, Marsha Guess, Kathleen Connell

10:45 a.m. - 11:00 a.m.

O-132: Proteomics and Pathway Analysis of Women With Mixed Urinary Incontinence-MUSA Supplementary (PRoMISe) Study
Maria Florian-Rodriguez, Gregory Keele, Megan Carnes, Heidi Harvie, Megan Bradley, Vivian Sung, Shawn Menefee, Nazema Siddiqui, Donna Mazloomdoost, Marie Gantz, Holly Richter

11:00 a.m. - 11:15 a.m.

O-133: Correlating Diffusion Tensor Imaging With Levator Ani Muscle Function In Young Women With and Without Pelvic Organ Prolapse
Hannah Zabriskie, Luyun Chen, Zoe Stukenberg, Eun-Kee Jeong, Carolyn Swenson

11:15 a.m. - 11:30 a.m.

O-134: Differential abundance of plasma microRNAs in baboons after induction of endometriosis
Ramanaiah Mamillapalli, Hanna Surmann, Niraj Joshi, Maria OchoaBernal, Gregory Burns, Asgi Fazleabas, Hugh Taylor

11:30 a.m. - 11:45 a.m.

O-135: Single-Cell Analysis Uncovers Divergent Cellular Landscapes of Eutopic and Ectopic Endometrium in Endometriosis
Xinyu Tang, Binya Liu, Alexis Combes, Brittany Davidson, Cheng Wang, Jingjing Li, Umair Khan,  Amber Casillas, David Stevenson, Camran Nezhat, Jessica Opoku-Anane, Jeanette Lager, Traci Ito, Deirdre Lum, Diana Atashroo, Tomiko Oskotsky, Juan Irwin, Marina Sirota, Linda Giudice

11:45 a.m. - 12:00 p.m.

O-136: An Organoid-Stroma Co-Culture Model to Define the Role of Leukemia Inhibitory Factor in Fertility.
Elizabeth Marr, Mariana Alonso-Riquelme, Manek Khedia, Manavi Vajhallya, Peter Movilla, Juan Gnecco

Placenta III

Moderators:
Craig Bierle, PhD
Rahul D'Mello, MD, PhD

208

10:30 a.m. - 10:45 a.m.

O-137: Spatial transcriptomic reveals cell specific placental changes induced by spontaneous birth in Term vs Preterm pregnancies
Jessica Weng, Jade Rechtzigel, Elizabeth Enninga, Sylvie Girard

10:45 a.m. - 11:00 a.m.

O-138: Mechanistic Insights Into Bacterial Extracellular Vesicle-Mediated Modulation Of Trophoblast and Immune Function In Vitro.
Hannah Wein, Marek Zygmunt, Damián Muzzio

11:00 a.m. - 11:15 a.m.

O-139: Predicting Stillbirth Risk Factors with Ultrasound Texture Analysis and Doppler Imaging of the Placenta
Adrienne Scott, Erin Louwagie, Edward Chandler, Samyuktha Kolluru, Caroline Fosher, Abigail Arter, Fran Manyx, Ulugbek Kamilov, Anthony Odibo, Michelle Oyen

O-140: Placental Nano- and Microplastic Burden Maps Immunomodulatory Niches Associated with Preterm Birth Risk Across 3.79 Million Spatial Transcriptomes
Enrico Barrozo, Myla Stanford, Audra Lane, Michael Jochum, Charlotte Kim, Cynthia Shope, Marcus Garcia, Rama Gullapalli, Emily Phan, Laurissa Barela, Emily Ricco, Daniel Kraushaar, Matthew Campen, Kjersti Aagaard

11:30 a.m. - 11:45 a.m.

O-141: PFBS Disrupts Mitochondrial Function and Induces Preeclampsia-Like Signatures in Human Placental Models
Namya Mellouk, Jie Zhou, Askar Takhirov, Danny Schust, Liping Feng

11:45 a.m. - 12:00 p.m.

O-142: Longitudinal MRI Comparison of Placental Inflammation and Oxygenation Profiles in Spontaneous Preterm Pregnancies
Zezhen Xiang, Qiuchang Sun, Peinan Zhao, Alison Cahill, Qing Wang, Yong Wang

Reproductive Biology III

Moderators:
Sonia Herraiz, PhD
Margeaux Marbrey, PhD

104

10:30 a.m. - 10:45 a.m.

SRI-Bayer President's Presenter Award
O-143: Interleukin-33-Activated Regulatory T Cells in Endometriosis Pathophysiology
Alexandra Wodz, Katherine Zutautas, Dan Vo, Chandrakant Tayade

10:45 a.m. - 11:00 a.m.

O-144: Everlasting Ovaries: Oogenesis Establishment in Naked Mole-Rats
Odei Barreñada Taleb, Peng Xinye, Rochelle Buffenstein, Melissa Holmes, Miguel Brieño-Enriquez

11:00 a.m. - 11:15 a.m.

O-145: Molecular Signature of Human Endometrial Stem/progenitor Cells at the Single Cell Level
Caroline Gargett, Harriet Fitzgerald, Sally Mortlock, Fiona Cousins, Brett McKinnon, Luk Rombauts, Jim Tsaltas, Grant Montgomery

11:15 a.m. - 11:30 a.m.

O-146: Determining the Enzymes Responsible for Decreased Endocannabinoids in Preeclampsia
Isha Sanghvi, Jennifer Sequoia, Virginia Winn

11:30 a.m. - 11:45 a.m.

O-147: Characterizing the steroid metabolome between users and non-users of hormonal birth control
Eva Siegel, Lauren Houghton, Mary Beth Terry, Kathleene Ulanday

11:45 a.m. - 12:00 p.m.

O-148: Normal Placental Architecture and Transcriptional Profiles Following Autologous CD133+ Bone Marrow-Derived Stem Cell Therapy in Asherman's Syndrome
Maria Pardo-Figuerez

Preeclampsia II

Moderators:
Jeffrey Denney, MD, MS, FACOG
Molly McAdow, MD, PhD

209

10:30 a.m. - 10:45 a.m.

President's Presenter Award
O-149: Liquid Biopsy Through Maternal Plasma Cell-Free RNA Enables Early Prediction of Preeclampsia Subtypes
Nerea Castillo-Marco, Marina Igual, Teresa Cordero, Irene Muñoz-Blat, Ángela Gaspar-Gómez, Neus Bernat-González, Sheila Ortega-Sanchís, Carbajo-García María Cristina, Carla Montagud-Almarcha, Carla Gómez-Álvarez, Érika Ortiz-Domingo, Alba Vives, Rogelio Monfort, PREMOM consortium, Carlos Simón, Tamara Garrido-Gómez

10:45 a.m. - 11:00 a.m.

President's Presenter Award
O-150: Dose response relationship of aspirin for prevention of preeclampsia: A systematic review and meta-analysis of randomized trials
Giulia Bonanni, Faezeh Aghajani, Samaneh Saraeian, Kamyar Ebrahimi, Izat Khawajah, Kjersti Aagaard, Vincenzo Berghella, Alireza Shamshirsaz

11:00 a.m. - 11:15 a.m.

O-151: Urinary Podocyte Enumeration: a Non-Invasive Assay for Early Prediction of Preeclampsia
Yuan Zhong, Chun-Li Chang, Edward Boumil, Kathryn Gray, David Haas, Lee Shulman, Cagri Savran

11:15 a.m. - 11:30 a.m.

O-152: Preeclamptic B Cell Adoptive Transfer During Pregnancy Causes Postpartum Hypertension
Nathan Campbell, Miriam Hankins, Murphy Lemon, Alexandra Demesa, Baoying Zheng, Rachael Morris, Babbette LaMarca

11:30 a.m. - 11:45 a.m.

O-153: The Potential Role of Disrupted Blood-Brain Barrier, Transcriptional Changes of the Neurovascular Unit and Dysfunctional Astrocyte Activity on Cerebral Complications of Preeclampsia.
Valentina Bucher, Owen Herrock, Erika Lucente, Sanketa Raut, Veronika Golubinskaya, Maryam Ardalan, Catherine Cluver, Louise Adermark, Joakim Ek, Lina Bergman

11:45 a.m. - 12:00 p.m.

O-154: Wildfire Smoke Exposure Increases Risk For Hypertensive Disorders Of Pregnancy
Samantha Piekos, Qi Wei, Michael Strasser, Jennifer Hadlock

Maternal Biology and Health II

Moderators:
Liliya Yamaleyeva, MD, MS
Antonina Frolova, MD, PhD

102

10:30 a.m. - 10:45 a.m.

O-155: Impact of Obesity on Maternal Cardiac Geometry and Function Pre-Pregnancy, During Gestation, and Three Months Postpartum in Sheep
Olga Patey, Rachael Crew, Anna Cochrane, Skaai Davison, Sage Ford, Clement Cahen, Youguo Niu, Dino Giussani

10:45 a.m. - 11:00 a.m.

Early Career Investigator Award
O-156: Proteomic signatures in women with pregnancy complications reveal future health risk.
Lucy Bartho, Susan Walker, Teresa MacDonald, Danica Idzes, Ping Cannon, Tuong-Vi Nguyen, Gordon Smith, Steve Charnock-Jones, Stephen Tong, Tu’uhevaha Kaitu’u-Lino

11:00 a.m. - 11:15 a.m.

O-157: Changes in Uterine Contractility with Age and Postpartum Recovery
Mari Domingo, Ashley Cua, Raffaella De Vita, Kristin Miller

11:15 a.m. - 11:30 a.m.

O-158: Transforming Conversations into Community-Informed Solutions for Maternal Health
Adetola Louis-Jacques, Estefania Ferrer, Noralbis Barrientos, Abigail Perret-Gentil, Adriana Menendez, Julia Rainer, Seun Ajoseh, Victoria Evans, Corinne Catham, Deepthi Varma

11:30 a.m. - 11:45 a.m.

O-159: Longitudinal Profiling of IgG and IgA Glycosylation in Pregnancy Reveals Associations With BMI, Number of Pregnancies and Conception Mode: The Rotterdam Periconception Cohort
Lotte Voskamp, Anna Daniels, Melek Rousian, Mandy van Hoek, Manfred Wuhrer, Régine Steegers-Theunissen, A.H. Danser, Koen Verdonk

11:45 a.m. - 12:00 p.m.

O-160: Natural Antibodies, Complement, and Follicular Dendritic Cells Cooperate to Promote Glycan-Mediated Maternal B Cell Tolerance to the Allogeneic Fetus.
Akanksha Onkar, Sydney Wren, Omar Valdez, Gabrielle Rizzuto, Susan Fisher, Adrian Erlebacher

12:15 p.m. - 1:15 p.m.

Moderators:
Marianna Alperin, MD, MS
Helen Jones, PhD

Ballroom A

12:15 p.m. - 12:30 p.m.

O-161: Parent-of-Origin Genetic Effect on Human Placental Methylation and Gene Expression  (Was LB-S-010)
Richard Biedrzycki, Tesfa Habtewold, Prabhavi Wijesiriwardhana, Kunal Kathuria, Fasil Tekola-Ayele

12:30 p.m. - 12:45 p.m.

O-162: Placental mitochondrial protein expression in maternal obesity: sex-specific adaptations independent of fetal overgrowth  (Was LB-S-008)
Toshihide Sakuragi, Fredrick Rosario, Theresa Powell, Thomas Jansson

12:45 p.m. - 1:15 p.m.

Awards Ceremony
Supported in part by the SRI Foundation

• President's Presenter Awards
• SRI-Bayer President's Presenter Awards
• Early Career Investigator Awards
• The Carole Mendelson Award
• The Robert N. Taylor Award
• Laxmi Baxi Award
• The Kusum Lata Excellence Award
• Poster Awards